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What does systemic mean?

Looking for the meaning or definition of the word systemic? Here's what it means.

Adjective
  1. Embedded within and spread throughout and affecting a whole system, group, body, economy, market, or society.
  2. (physiology) Pertaining to an entire organism.
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Examples
The commonest causes of vasculitic ulcers are rheumatoid arthritis, systemic lupus, and polyarteritis nodosa.
Society's methodical and systemic ideals stand challenged wherever individual freedom is put under any restraint.
However, some lentigines are associated with systemic abnormalities, in addition to the dermatologic manifestations.
Conversion to zero-grazing would represent a complete and expensive systemic change for the Irish farmer.
Typically, there is no problem with the dentist, but do your best to avoid systemic anesthetic gas.
The current surgical procedures for lung transplantation do not reinstitute the systemic circulation of the graft.

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