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What does severe mean?

Looking for the meaning or definition of the word severe? Here's what it means.

Adjective
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Ebola hemorrhagic fever is a severe, often-fatal disease that affects humans and non-human primates, such as monkeys, gorillas and chimpanzees.
These lights enhance your visibility especially in severe weather conditions.
The rules for success in the last bull market do not apply to this severe bear market.
The duodenal mucosa showed severe villous atrophy but no subepithelial collagen deposition.
The splenic artery was encased by tumor, although there was no intraluminal invasion, and the artery showed severe calcific atherosclerosis.
I explained to him that it was more of a severe sprain than an actual fracture and prescribed a wrist splint to be worn for the next three weeks.

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