| He also said that mutations in non-coding portions of the gene, which control regulation, could also render it nonfunctional, which tends to push the number upward. |
| Type O is a nonfunctional allele, because it does not recognize the enzyme substrate. |
| When the Y fragment is minimal and nonfunctional, the child is usually a girl with the features of Turner syndrome or mixed gonadal dysgenesis. |
| One mutation, C282Y, disrupts an intramolecular disulfide bridge and renders the protein nonfunctional. |
| The research found that a majority of government-led initiatives on youth are largely nonfunctional, non-participatory, short lived or driven by the calculation of immediate political gains. |
| The patients underwent the new bypass coaptation procedures with complete or partial return of motor and sensory function, which otherwise would be totally nonfunctional. |
