| More studies are required before any recommendation can be made about the use of isoflavones to treat cyclical mastalgia. |
| The chaste tree is known to treat the irregularity of menstrual cycle, relieve mastalgia and premenstrual syndrome. |
| The use of a well-fitting bra that provides good support should be considered for the relief of cyclical and noncyclical mastalgia. |
| Evidence on the effect of Vitex agnus and Flaxseed on cyclical mastalgia is not enough. |
| Two RCT's74,75 found tamoxifen superior to placebo in premenopausal women with cyclic or noncyclic mastalgia. |
| Also, a higher proportion of patients with idiopathic granulomatous mastitis presented with acute onset mastalgia. |
