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What does markedly mean?

Looking for the meaning or definition of the word markedly? Here's what it means.

Adverb
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Examples
And here was me assuming the locale would be markedly friendlier than the Bronx.
She also was noted to have a markedly thickened calvarium on both radiographs and computed tomographic scan at 6 years old.
It is quadrangular in outline, with a markedly convex lateral surface perforated by the coracoid foramen.
These immigrants, the Yayoi, were agriculturalists whose physical traits differed markedly from the Jomon.
Thermal and textural anomalies seen on the surface of the lava domes change markedly during the restive state prior to larger eruptions.
The role of the publisher could change markedly and perhaps be collapsed into that of the writers and their business managers and agents.

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