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What does lose it mean?

Looking for the meaning or definition of the word lose it? Here's what it means.

Verb
  1. (informal) To be explosively angry; to lose one's temper.
  2. (informal) To begin to laugh uncontrollably.
  3. (informal) To lose one's mind, go crazy.
  4. (informal) To cease to have a skill or ability, to lose one's touch, to be washed up.
  5. (idiomatic) To lose control of a situation. (Can we add an example for this sense?)
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