| Significant levels of losartan and its active metabolite were shown to be present in rat milk. |
| Use of losartan should include appropriate assessment of renal function. |
| Both biliary and urinary excretion contribute substantially to the elimination of losartan and its metabolites. |
| Much of the global growth was due to strong performance by the recent launches of losartan and metaxalone and the continued performance from tacrolimus. |
| The present data showed blood pressure reduction and no reversal of the hyposensitivity of the baroreflex by acute losartan treatment. |
| Neither losartan nor the active metabolite can be removed by hemodialysis. |
