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What is an inactivation?

What is an inactivation? Here are some definitions.

Noun
  1. the process of rendering something inactive
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Examples
However, the sodium channel inactivation gates are open in the hyperpolarized virtual anode region, causing the tissue to be excitable.
My results suggest that the inactivation of nisin by the producer organism may not be entirely enzymatic.
In mammals, methylation is required for essential developmental programs including X chromosome inactivation in females and genomic imprinting.
Several forms of cancer involve the inactivation of the apoptotic process, thus enabling the cancer cells to continue to proliferate.
Phototreatment by sensitizers is a method being investigated for virus inactivation of blood products.
The state of gene inactivation is inherited epigenetically through multiple mitoses.

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