| An uncommon blood disease called paroxysmal nocturnal hemoglobinuria can cause blood clots in the liver, the spleen or beneath the skin. |
| In elderly, asplenic, or immunocompromised patients a severe malaria-like illness with hemoglobinuria, hemolytic anemia, and renal failure can occur. |
| His book chronicles a young doctor's battle with a rare and life-threatening blood disease, paroxysmal nocturnal hemoglobinuria. |
| In this setting, a serum sample with normal color indicates myoglobinuria, whereas a pigmented brown or red serum sample indicates hemoglobinuria. |
| Rarely, hemoglobinuria, hematuria, interstitial nephritis, renal insufficiency, acute tubular necrosis and acute renal failure have been noted. |
| Hemoglobinemia, hemoglobinuria and subsequent hyperbilirubinemia are usually detectable. |
