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What is a dysregulation?

What is a dysregulation? Here are some definitions.

Noun
  1. (biochemistry) A failure to regulate properly.
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Experts now recognize that depression is a multifaceted disorder with dysregulation in a number of different systems.
It offers a child a safe haven from which to explore feelings, behaviors and issues ranging from self-esteem to severe emotional dysregulation.
Postpartum dysregulation of the thyroid gland has been considered as another possible cause of depression.
Addiction can be viewed as a dysregulation of brain reward systems resulting in compulsive use and loss of control over drug taking.
They are interested in how the dysregulation of different aspects of RNA metabolism contributes to cells becoming cancerous.
Surgical excision has the potential risk of rendering a child athymic and prone for developing immune dysregulation and immunodeficiencies.

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