| Leukemia lines resistant to either doxorubicin, vincristine, methotrexate, or hydroxyurea were tested. |
| Cytotoxic antibiotics, such as doxorubicin, stick to DNA causing it to become tangled and preventing the cell from dividing. |
| The patient completed 4 cycles of combination chemotherapy consisting of cyclophosphamide, doxorubicin, vincristine sulfate, and prednisone. |
| Human lung-cancer cells were treated with the chemotherapeutic agent doxorubicin, which causes cellular DNA damage. |
| Most standard protocols use doxorubicin and cisplatin, with or without high-dose methotrexate, for both induction and adjuvant chemotherapy. |
| Trials have demonstrated threshold dose effects for two of the most active chemotherapeutic agents, doxorubicin and cyclophosphamide. |
