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What is a distemperature?

What is a distemperature? Here are some definitions.

Noun
  1. (now rare) A state of adverse or unhealthy atmospheric conditions.
  2. (now rare) Unhealthy imbalance of bodily humours; a disorder.
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By this distemperature of weather, much cattle perished, much corn upon the ground was either destroyed, or greatly empaired.
Then, in addition to these absolute weaknesses, come the disproportions of the body, the distemperature of various organs.
A slight incident occurred, however, which sprinkled a little patience on the heat of his distemperature.
Many and various were the conjectures of the guests, concerning a distemperature which seemed rather mental than corporeal.

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