| Examples of sulfonylureas include tolbutamide, chlorpropamide, glyburide and glipizide. |
| First generation sulfonylureas, like chlorpropamide, should generally be avoided due to active metabolites and hypoglycemia risk. |
| The first-generation sulfonylureas currently available are chlorpropamide, tolazamide, and tolbutamide. |
| Pharmaceuticals include a class of oral medications used to stimulate the beta cells to release more insulin, such as sulfonylureas, meglitin ides, and chlorpropamide. |
| In contrast, patients receiving chlorpropamide or glibenclamide gained an average of 3 to 4 kg, while insulin treated patients gained approximately 6 kg. |
