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What is a chancre?

What is a chancre? Here are some definitions.

Noun
  1. (pathology) Skin lesion, sometimes associated with certain contagious diseases such as syphilis.
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Examples
In addition, the spirochetes can be viewed by examining fluid from the primary chancre or secondary lesions under the microscope.
In those not previously exposed to M. tuberculosis, miliary tuberculosis of the skin and tuberculosis chancre have been described.
Secondary syphilis develops several weeks to months after the chancre appears.
It may be a chancre, and it may be exceedingly serious if not properly diagnosed.
The chancre enlarges and often breaks in the centre, leaving a shallow ulcer.
This chancre may look like a pimple, blister, or open sore and usually appears in the genital area.

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