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What are antagonists?

What are antagonists? Here are some definitions.

Noun
  1. plural of antagonist
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Thus, when the culture wars began in the late 1960s, the antagonists of a traditional curriculum were pushing against an open door.
But, as fate would have it, Darcy was called home early, and the two old antagonists once more confronted each other.
Most of these countries, of course, are traditional adversaries or antagonists.
The name of Middleton was unpopular, and his proscription very naturally tempted me to peruse his writings and those of his antagonists.
Leukotriene inhibitors and leukotriene-receptor antagonists are effective in the treatment of inflammatory diseases such as asthma.
As ultimate commander of the military, he must now move decisively and evenhandedly to disarm the antagonists.

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