Conventional amphotericin B deoxycholate has long been used, but is limited in efficacy and has significant toxicity. |
Itraconazole treatment was started, but it was switched to amphotericin B after 3 weeks because local symptoms persisted. |
With some precautions and proper management, all patients of kala-azar could be cured with amphotericin B in a rural set-up. |
An attractive alternative to amphotericin is the triazole voriconazole. |
The intravenous and oral formulations are used for the treatment of aspergillosis in patients who are intolerant of or who are refractory to amphotericin B therapy. |
Of the three adults who received amphotericin B in addition to stopping the lipid alimentation, one had persistent fungemia and died of a cardiac arrest. |