Abetalipoproteinemia is a rare disease in which apo B is not synthesized, preventing lipoproteins containing this apolipoprotein from being formed. |
Role of apolipoprotein E-containing lipoproteins in abetalipoproteinemia. |
In contrast, parents of patients with abetalipoproteinemia usually have normal apo B concentrations, because it is an autosomal recessive disorder. |