How to use vivo in a sentence

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Sentence Examples Measurement of the retinal arterioles offers a non-invasive means to evaluate systemic associations of the human microcirculation in vivo. Bursting has also been recorded in vivo, where it can be directly observed to exert negative feedback on plasma glucose levels. All are capable of intensifying oxyradical generation in vivo and depleting tissue antioxidant stores. The final movement, Molto vivo, reveals the interest Bloch developed in Far eastern music. In vivo cytogenetic studies suggested the induction of chromosome damage in Chinese hamster bone marrow cells. It was found that a combination of cobalt or iron phthalocyanine and sodium ascorbate has high in vitro and in vivo antitumor activity. Mysliwy et al. reported the formation of NPYR from sodium nitrite and pyrrolidine in vivo in dog stomach. Good correlation exists between findings in vitro and the observed contractile properties in vivo. Some of the triterpenes fractions have been thought to act as in vivo precursors to steroids. In vivo, the repression of genes involved in starch biosynthesis has been reported to block pollen development. Because of the small size of the domains, advanced biophysical in vivo techniques are required for their identification and detailed study. With transfected cells grown as solid tumors in vivo, the bioluminescence light is emitted shortly after systemic administration of luciferin. Most studies that report in vivo bioluminescence emission spectra or describe the color of bioluminescence only deal with the adults. The results also suggest the possibility of transport of small molecules within and along tendons in vivo. Ideally we would want to replicate the in vivo conditions and mimic the outcome of nuclear division in vivo. Instead, the animal airway tissue in vivo has obviously been depleted of its eosinophils by their egression into the airway lumen. He is working on a project with a novel approach to track neural stem cells in vivo. For the in vivo part of this study, cutaneous blood vessels of the hamster dorsal skin flap model were used. Eosinophils in vitro exhibited different stages of apoptosis, ending with secondary necrosis distinct from in vivo eosinophil cytolysis. These findings suggest a need for in vivo studies with this combination in preclinical prostate cancer models. Show More Sentences Purines and pyrimidines are considered as complex molecules themselves because they are never synthesized as such in vivo. However, it is generally recognized that this assumption is applicable to virtually no solid tumor growing in vivo. Future studies should reveal other types of well-defined structure-function correlations for transfection in vivo in the presence of serum. Rabies virus presents strict neurotropism in vivo, but it can also infect non-neuronal cells in vitro. Animal trials confirmed the suppression of tumorigenicity of cancer cells by ex vivo delivery. Resin plates were contaminated in vivo upon intraoral use by 10 volunteers for 7 nights. Significantly, their findings were supported by both in vivo and in vitro experiments using reference mutagens. In vivo the pessary demonstrated high contraceptive efficacy in rabbits of proven fertility. In vivo, the diaphragm does not perform maximum isometric contractions but shortens against a submaximal load. We aim to recruit a post-doctoral scientist to work on a research programme on autophagy and neurodegeneration using in vivo approaches in mice. The enzyme, hen egg lysozyme, has not been shown to form fibrils in vivo, and only mutants have been associated with amyloid-related diseases. Evidence pointed out that the DNA sequence in vivo is a determinant of nucleosome occupancy at promoters. We investigated a role of the glyoxalase detoxification system of precursor reactive carbonyl compounds in the in vivo AGE formation. There has been no proof in clinical trials that squalamine has benefits in the in vivo setting. In vivo studies have demonstrated that glutamine is essential for optimal immune cell functioning for monocytes, lymphocytes and neutrophils. There is little information available on the feasibility of transdermal iontophoretic delivery of anticancer agents in vivo. Because the oleoresin of resin vesicles is a low-viscous liquid, it can be detected by high-resolution C MAS NMR spectra in vivo. The use of chloral hydrate should be avoided in studies exploring the in vivo responses to sialagogues. The assembly of sickle hemoglobin requires high hemoglobin concentrations in vivo and in phosphate buffers of low molarity. Localized observation of blood vessel stasis, occlusion or vessel dilation have all been observed with Photofrin treatment in vivo. Show More Sentences Microspores cultured in vitro in a rich medium develop into mature pollen grains, which are fertile upon pollination in vivo. A feature shared by senescent cells in culture and in vivo is shortening of the telomeres. The locations of two mutations that could not be recovered in vivo are indicated by solid stars. In contrast, a significant reduction of the thrombogenicity in vivo was observed at 6 and 24 hours on diphenhydramine pretreatment. Those experiments were conducted in the absence of the mechanical forces that may act on molecules during function in vivo. Fortunately, the inhibitory salt effect can be alleviated in vivo by natural DNA supercoiling. Another factor that may limit uptake of the radiopharmaceutical is the transient nature of the tracer bolus presented to the cells in vivo. The biogenesis of microtubules in vivo consists of a cascade of sequential reactions. To create an in vivo code, highlight the word or short passage that strikes you as significant and from which you want to create a node. The behaviour of pigment metabolism mutants is consistent with a similar function for chlorophyll as a protein protectant in vivo. Niacinamide inhibits free radical formation and facilitates beta-cell regeneration in vivo and in vitro. Rapid corticosteroid effects have also been seen in neurons of the rostral ventrolateral medulla recorded in vivo. Excess linoleic acid has produced inhibitory effects on in vivo prostaglandin synthesis. However, the function of this positive feedback loop in vivo is not clear. Can similar conformational transitions occur in vivo, for example, during exocytotic swelling of secretory granules or in a stretched fibronectin matrix? Second, an IC 50 cut-off greater than 100m M is said to be related to the need for there to be a relationship between in vitro and in vivo potency. Many peptides and proteins interact strongly with amphiphilic molecules and these interactions are of vast importance, not only in vivo but also in technical applications. Abp1 also might function to attenuate stronger NPFs in vivo. The in vitro and in vivo experiments showed that free cholesterol and phospholipids were transferred from lipid emulsion to plasma lipoproteins independently from each other. Finally a dedicated software, interfaceable with record and verify systems used in the centers, was developed to obtain in vivo dosimetry results in less than 2 min after beam delivery Show More Sentences The abscission process was also induced in vivo by embrioctomy or 2-chloroethyl phosphonic acid treatment in fruitlets and by deblading in leaves. Two case studies have been published on in vivo iontophoretic targeting of cytostatic drugs into skin tumors, one on Bleomycin and the other on Cisplatin. The similar pH response of root exudate and sap collected by shoot pressurization suggests that xylem sap of N-deprived Capsicum plants is indeed more alkaline in vivo. Transgenic selection assays provide a unique opportunity to study the mechanisms of mutagenicity in different somatic and germinal tissues in vivo. It has developed proprietary monoclonal antibodies to properdin that are potent in vitro and in vivo inhibitors of the complement alternative pathway. Although the sulfated maitake fraction resembled the anti-HIV potency of AZT, it was not considered a promising treatment because of potential cellular toxicity in vivo. Finally, the in vivo catalytic activities of eukarytotic type IA topoisomerases, the topoisomerase III from various higher organisms may be related to their sequences. Transgenic DNA constructs have been used to rescue mutant genes, express reporter genes, and test the relationship of gene structure and function in vivo. There is now an extensive literature based on in vivo and in vitro studies that deal with mechanistic aspects of xanthophyll pigment-dependent photoprotection. All of these require metabolism to form genotoxic metabolites in vivo. The membrane potential responses and firing patterns of rat thalamic neurons evoked by iontophoretically applied excitatory amino acids were recorded in vivo. In addition to testing the generality of fungal survival factors, auxotrophic mutants allow several key aspects of fungal biology to be assessed in vivo. During in vivo measurements, excitation light is incident upon the epithelium, and must travel through this tissue layer before reaching the stroma. Such homotypic and heterotypic aggregates in vivo often regulate the progress of inflammatory diseases, cardiovascular ailments, and cancer metastasis. Growth cones isolated from their cell bodies are able to navigate correctly along the visual pathway in vivo and to respond chemotropically to guidance factors in vitro. This new technology, an imaging method known as in vivo bioluminescence, enables investigators to track changes in the viral population in the same animal day after day. However, it will be necessary to ensure that the shock-wave parameters needed for effective cell permeabilization do not cause unacceptable tissue damage in vivo. Victor Oreffo presented results on gene expression analysis following in vivo or in vitro exposure to the oxidative stress agents menadione and diquat. A growing body of in vitro and in vivo research shows Aloe vera has significant antidiabetic activity. Antitumoral and antioxidant effects of a hydroalcoholic extract of cat's claw in an in vivo carcinosarcoma model. Show More Sentences Comparative estrogenicity of estradiol, ethynyl estradiol and diethylstilbestrol in an in vivo, male sheepshead minnow, vitellogenin bioassay. It inhibited muscular fatigue in both in vitro and in vivo studies, similar to the activity of ibogaine. The trophoblast marker genes, cytokeratin 8 and 18, showed lower expression levels in the SCNT blastocysts compared with in vivo blastocysts. Several in vitro and ex vivo investigations addressed the mechanism of FAE action. Many different allylic pyrophosphates are effective initiators, but FPP seems to be the one primarily used in vivo. Now, Teicher and her colleagues have discovered striking differences between chemotherapy resistance in vivo and in vitro. Less virus was transmitted by mosquitoes in vivo than was found for comparable times of salivation in vitro. The third element involved years of assay standardization, replication of results in multiple laboratories, and comparisons with in vivo results. Alternatively, we propose to modify the Ad capsid or LV envelope using epitopes identified by in vivo biopanning that bind to PR and. Antrodia camphorate inhibits proliferation of human breast cancer cells in vitro and in vivo. The grant is repayable once revenues are generated from sales of ex vivo IL-10 gene therapy. Sister chromatid exchange and chromosome aberrations induced by curcumine and tartrazine on mammalian cells in vivo. Words that apply to the characteristic movement, such as maestoso, scherzando, vivo, mesto, etc. Relative binding affinity-serum modified access assay predicts the relative in vivo bioactivity of the xenoestrogens bisphenol A and octylphenol. In vivo analysis revealed that depolymerized scleroglucan leads to improved moisturizing properties and improved skin feeling. University of Michigan has patented methods for the ex vivo formation of mammalian bone and subsequent uses of the bone. The Mantoux test is an in vivo delayed hypersensitivity response to purified peptide derivative. Extracellular calcium elicits a chemokinetic response from monocytes in vitro and in vivo. In vivo dynamics of the microparasite Perkinsus marinus during progression and regression of infections in eastern oysters. The capabilities an ELN must have are unlike those needed for chemistry or in vivo biology. Show More Sentences The effect of MTX-induced adenosine release has been studied in a number of in vivo models. In vivo inhibition of foam cell development by probucol in Watanabe rabbits. They confirmed experimentally in vivo and in vitro that decreasing pH increases the sensitivity of the acinar cells to zymogen activation. Daynes RA, Dudley DJ, Araneo BA Regulation of murine lymphokine production in vivo. Differential oligodendroglial expression of the tumor necrosis factor receptors in vivo and in vitro. Improved in vitro embryo development using in vivo matured oocytes from heifers superovulated with a controlled preovulatory LH surge. Twenty-three of the lungs were selected to undergo the new technique, which is known technically as normothermic ex vivo lung perfusion. A major difference between in vivo and in vitro conditions is the crowdedness of the cytoplasm and biological membranes. Chronic treatment with interleukin-1 induces coronary intimal lesions and vasospastic responses in pig in vivo. Human placental extract, in vivo and in vitro assessments of its melanocyte growth and pigment-inducing activities. Developmental exposure to a commercial PCB mixture produces a persistent impairment in long-term potentiation in the rat dentate gyrus in vivo. Famciclovir is a prodrug that is converted in vivo to penciclovir, the active antiviral agent. The researcher is therefore able to quantify biological targets and fluorescent agents to the picomole in vivo and in real time. We have undertaken to study the effect of pentachlorophenol on invertebrate and vertebrate cells in vitro and in vivo. First, gypsum is resorbed too quickly in the body, and second, is shown to be ineffective in taking part in in vivo bone remodeling processes. Treatment of mice with a hepatotoxin leads to increased adenosine release from liver slices cultured ex vivo. Translational step inhibited in vivo by aflatoxin B1 in rat-liver polysomes. Under in vivo condition, polyspermy is controlled in part by the regulatory role of the oviduct. Excitatory action of lead on rat sympathetic preganglionic neurons in vitro and in vivo. The in vitro organic matter degradability was always lower than in vivo digestibility, while the two trends were almost superimposable. Show More Sentences The grand finale experiment, performed ex vivo with cells from two aviremic patients, addresses this question. Bone uptake was relatively low, suggesting no in vivo defluorination of the tracer. ReaDMe has the ambitious goal to systematically define the sensitivity of TFs to local levels of DNA methylation in vivo. Researchers used ex vivo nephroureterectomy specimens to obtain tissue samples for biopsy. The secretability of R5-6 would be important for future in vivo gene transfer studies. Perfluorooctane sulfonate affects hormone receptor activity, steroidogenesis, and expression of endocrine-related genes in vitro and in vivo. Highly malignant MSDACs that were derived from metastatic sites exhibited CSC status and exerted robust tumorosphere formations ex vivo. Evidence for two autonomous transactivation functions and heterodimerization in vivo. However, formation of quinoid metabolites of black cohosh was demonstrated only in vitro but not in vivo. In the present study, the antiplatelet and antithrombotic activities of indole-3-carbinol were investigated in vitro and in vivo. Cinchonine, a potent efflux inhibitor to circumvent anthracycline resistance in vivo. In vivo anomalous diffusion and weak ergodicity breaking of lipid granules. Doing so would help pinpoint the role of macrophages in erythroblastic islands in vivo. These mice were examined using manganese-enhanced MRI to assess effects of PBM on transretinal calcium channel function in vivo. We and others previously showed that progestins promote the growth of human breast cancer cells in vitro and in vivo. In vitro percutaneous absorption studies and in vivo evaluation of anti-inflammatory activity of essential fatty acids from fish oil extracts. To this end, we will apply in vivo experimental evolution to mutualistic bacteria, using gnotobiotic animal models. Assessing environmental chemicals for estrogenicity using a combination of in vitro and in vivo assays. In vivo optical detection of cancer using chlorin e6-polyvinylpyrrolidone induced fluorescence imaging and spectroscopy. Direct measurement of in vivo secretion of pig thyrocalcitonin by radioimmunoassay. Show More Sentences Overexpressing centriole-replication proteins in vivo induces centriole overduplication and de novo formation. In addition to bacterial assays, MX is a direct-acting mutagen and genotoxin in vivo and in mammalian cells in vitro. In vivo inhibition of acetylcholinesterase and aliesterases by the five compounds was determined for both species. Efficient oncolysis by a replicating adenovirus in vivo is critically dependent on tumor expression of primary ad receptors. Increased expression in vivo of VCAM-1 and E-selectin by the aortic endothelium of normolipemic and hyperlipemic diabetic rabbits. The claims describe methods of using the reovirus ex vivo to eliminate contaminating cancer cells from autologous blood stem cell transplants. Trypanolytic activity in vivo of plasma from patients with schistosomiasis against the African trypanosome, Trypanosoma brucei brucei. The claims cover methods of selectively removing cancer cells ex vivo from blood stem cells and other organs using reovirus. Ptx3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization. However, they are subject to some in vivo degradation mechanisms. Enhancement of dye-sensitized phototoxicity to house fly larvae in vivo by dietary ascorbate, diazabicyclooctane, and other additives, Pesticide Biochem. Further specificity analysis reveals a subset of functional antibody clones capable of recognizing the rodent ortholog of the target, enabling in vivo pharmacology studies. Unlike earlier generation chelates used to attach the yttrium radioisotope to antibodies, the MX-DTPA used to create IDEC-Y2B8 exhibits excellent in vivo retention of yttrium. In vitro as well as in vivo chaperonins, either alone or with other chaperones and ATP, have been shown to orchestrate the re-folding of partially denatured proteins. This may indicate that lignin-modifying enzymes in vivo are not able to depolymerise PSS, and perhaps also do not efficiently decompose other unreactive synthetic polymers. Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets. The first evidence to establish that in vivo involvement of adenosine receptors in the mechanism of action of methotrexate is from the same murine air pouch model. Drosophila is a powerful model organism to discover gene networks and test gene function in vivo, and has recurrently led to discoveries relevant to human health. Additionally, the single-cell transcriptome analyses of clonally related cells in vivo will provide unique insights into the clonality of gene expression per se. Thus, appropriate degumming and sterilization will assure the biocompatibility of silk fibroin, which is further validated by in vivo experiments on rats and pigs. Show More Sentences The central role of thromboxane and platelet activating factor receptors in ex vivo regulation of endotoxin-induced monocyte tissue factor activity in human whole blood. In vivo, dysregulation of enzymatic conversion of the cell membrane phospholipid sphingomyelin to ceramide by SMase leads to a change in ceramide concentration. In vivo assay and sequencing of the hemagglutinin protein cleavage site classified the virus as a North American genetic lineage of low pathogenicity for chickens. BioVec, LLC has patented methods and compositions for treatment of cardiovascular and peripheral vascular diseases using ex vivo and in vivo gene delivery technologies. In vivo antagonism with zidovudine plus stavudine combination therapy. Stabilization of recombinant avirulent vaccine strains m vivo. Effects of type and level of supplementation and the influence of the rumen pH on cellulolysis in vivo and dry matter digestion of various roughages. Fusion events in vivo, particularly in embryonic development, often involve the purse-string contraction of a pluricellular actomyosin cable at the free edge. Detection of in vivo genotoxicity of haloalkanes and haloalkenes carcinogenic to rodents by the alkaline single cell gel electrophoresis assay in multiple mouse organs. The model needs to be refined through controlled pH and the use of additional procalcifying agents other than Pi in order to reproduce calcium phosphate deposition in vivo. In conclusion, we find that the diffusible fraction of cTnT is likely to be substantially larger in vivo than previously reported and likely affected by the local plasma flow. The extent of the antioxidant potential of pycnogenol in vivo is unclear. Chapters look at hydrophilic, mineral and pyrolytic carbon coatings in and ex vivo orthopaedic applications and finally at surface modification and preparation techniques. Data demonstrate antitumor activity at well-tolerated doses of the inhibitor of fucosylation in several in vivo tumor models, including a syngeneic tumor vaccine model. Reducing plaque cellularity by the induction of apoptosis may be one mechanism by which Antrin photoangioplasty causes reduction of atherosclerotic plaque burden in vivo. Mouse mutants will be used to study the in vivo role of catalytic activity of piwi proteins in piRNA biogenesis and identify putative targets by transcriptomics approaches. Effects of the mycelial extract of cultured Cordyceps sinensis on in vivo hepatic energy metabolism and blood flow in dietary hypoferric anaemic mice. A commercially available dried extract of Japanese herbal prescription, Juzen-Taiho-To has been found to enhance functions of Peyer's patch cells in vitro and in vivo. In this study, we have evaluated its effect on LPS-induced leukocyte recruitment in vivo and the mechanisms involved in its anti-inflammatory activity. In vitro and in vivo activity of protein kinase C inhibitor growth delay in vivo chelerythrine chloride induces tumor cell toxicity and growth delay in vivo. Examples from Classical Literature Tamoxifen and flaxseed alter angiogenesis regulators in normal human breast tissue in vivo. When tested, Fision Hydrate proved to have immediate and long-term moisturizing properties based on in vivo studies. Recently, our laboratory reported, for the first time ever, that the curcumin affects sperm function in vitro and fertility in vivo. The object of this study was to compare the forms of fresh, silage and hay of caramba, with respect to their chemical composition, in vivo digestibility and ME values. Find more words! 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