| These cosolute molecules bathe and solvate the macromolecular solute as water does. |
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| Unsolvated and the various solvated forms of the same active moiety are generally considered identical, provided the solvate content is within acceptable levels. |
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| Under synthesis conditions darunavir appears as an ethanolate solvate pseudopolymorph, however a hydrate and an amorphous non-solvated form are also possible depending on the environmental conditions. |
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