Furthermore, the extent of photosensitizer distribution and penetration into the spheroids was examined. |
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The antitumor properties of St. John's wort are attributed to hypericin, which is a powerful photosensitizer. |
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Hypericin, a polycyclic quinone obtained from plants of the genus Hypericum, has been shown to be a promising photosensitizer. |
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The specificity of the PDT effect correlates with the distribution and concentration of the photosensitizer in the tumor. |
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For all formulations tested, uptake of photosensitizer into cells was dependent on concentration, time and temperature. |
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A low power laser warms the targeted tissue and releases a bolus of photosensitizer. |
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A photosensitizer that binds to the titanium allows the use of visible light for the process. |
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The combination of the laser and photosensitizer leads to localized destruction of tumor cells. |
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Furthermore, the combination of therapeutic laser light and a photosensitizer can achieve a bactericidal effect. |
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Once this excited photosensitizer encounters tissue oxygen, it will transfer its energy, forming a highly reactive singlet oxygen molecule. |
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They can serve as both a triplet photosensitizer and a hydrogen donor. |
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