| The arrow points to a mitotic figure cleaving off a narrow cell from a semi-regular hexagon cell. |
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| The structures of rearrangements were defined by mitotic chromosome staining as well as by genetic and polytene chromosome analysis. |
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| The mitotic activity was focally brisk, with an average of 8 to 10 mitoses per highpower field in these areas. |
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| After 10 mitotic divisions, the tip of the hypha bends to form a crozier into which migrates one nucleus of each mating type. |
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| Inside of this zone, undifferentiated xylem cells without secondary walls proliferated through mitotic activity. |
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| In mammals, germ cells undergo a small number of proliferative mitotic cell divisions as they migrate to the gonad. |
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| The phialides produce chains of uninucleate conidia after repeated mitotic division and cytokinesis. |
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| In the absence of mutation, homoplasmic cells produce only homoplasmic daughter cells after mitotic cell divisions. |
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| Each haploid cell undergoes a mitotic division to produce the generative and vegetative nuclei. |
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| Roots of this length have not initiated physiological death processes, and include a mass of mitotic cells. |
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| Kernel growth is supported by cell production through mitotic cell divisions. |
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| The most distal cells undergo mitotic proliferation and serve as a stem-cell population. |
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| Giant cell, fourth mitotic division showing replicated mirror image dicentric chromosomes and acentric fragments. |
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| Besides amitosis, cold-pretreatment also induced some abnormal mitotic behavior leading to the formation of micronuclei. |
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| Subsequently, one of the two mating-type alleles was lost during mitotic or meiotic divisions. |
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| During pachytene, the chromosomes are less condensed and much longer than in mitotic metaphases. |
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| The microtubules tie the chromosomes to the mitotic spindle during cell division. |
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| The spindle cells showed moderate nuclear pleomorphism and scattered mitotic figures. |
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| Bizarre cells, nuclear pleomorphism, and mitotic figures were easily found. |
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| Bone marrow cells exhibited chromosome aberrations, aneuploidy, and changes in the mitotic index. |
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| Staining was quantitated and correlated with histologic subtype and mitotic index. |
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| Radioiodine can cause significant apoptosis and mitotic cell death in the thyroid tissue. |
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| Based on these findings, it is reasonable to conclude that telomeric regions of mitotic chromosomes are not unusually susceptible to crossover. |
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| It is most likely that the nonmosaic tetraploidy of the neonate was caused by a cytoplasmic cleavage failure at the first mitotic division. |
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| Radiation inhibits mitotic activity in the germinal cells of the epidermis, hair follicles, and sebaceous glands. |
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| The problem is greatest at mitotic metaphase, when chromosomes are shortest and neighboring signals are thus closest. |
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| Only mononuclear protoplasts were capable of complete cell wall regeneration and mitotic division. |
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| Spermatogonia are the mitotic germ cells of the testis from which sperm arise by spermatogenesis. |
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| Moreover, tetraploid cells do not bud or show abnormal mitotic spindles when placed in water. |
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| A primary spermatogonium surrounded by a pair of cyst cells undergoes four mitotic divisions, forming a cyst of 16 primary spermatocytes. |
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| A critical step in the cell cycle is the proper attachment of chromosomes to the mitotic spindle during metaphase. |
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| Metaphase spindles with replicated mitotic chromosomes were assembled in meiotic Xenopus egg extracts as described. |
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| Poorly differentiated tumors show pleomorphic and hyperchromatic spindle-shaped cells with abundant mitotic activity. |
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| For immunolabeling, third instar mitotic squashes were prepared and hybridized as described. |
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| The lining cells showed no significant nuclear pleomorphism or mitotic activity. |
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| Microscopically, large neoplastic lymphoid cells with prominent nucleoli and frequent mitotic figures occlude small vessel lumina. |
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| Further, interphase nuclei appeared disintegrated and some mitotic figures were clumped together. |
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| No patients exhibited atypical mitotic figures in the cells of the epidermis, hair follicles, sweat glands or surrounding connective tissue. |
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| The transparent, 100-m-diameter oocyte is fertilized and undergoes rapid mitotic cleavage cycles. |
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| In contrast, the 12 essential genes known to exist within the mitotic heterochromatin of chromosome 3 have remained only imprecisely mapped. |
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| There a somatic genetic principle was established whereby mitotic chromosome replication produces sister chromatids that are different from one another. |
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| When microtubules are aligned end to end to form a mitotic spindle, the genetic material of the cell is attached to the spindle fibers, pulling and dividing the cell into two. |
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| Accurate separation of chromosomes by the mitotic spindle depends upon their connection to spindle fibers at a highly regulated location of each chromosome called the centromere. |
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| During cell division a pair of centrioles moves to each end of the cell, forming the poles of the mitotic spindle. |
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| After meiosis, the four meiotic products undergo an additional mitotic division to yield eight haploid nuclei, which differentiate into an octad of eight ascospores. |
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| This process is called mitotic slippage and yields tetraploid 4N cells. |
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| In all specimens, mitotic index was quantitated by counting the number of mitoses per twenty 100X oil immersion fields in areas of highest mitotic activity. |
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| Radiobiologists often distinguish between radiation-induced cell death with regard to the ability to enter mitosis, i.e. interphase or mitotic cell death. |
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| Excess nickel has a negative effect on plasma membrane polarization, ion uptake and translocation, cell mitotic activity, and carbon partitioning in roots. |
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| An obvious question is whether the mat bias is absent in azygotic meiosis after homologous chromosomes have coexisted in diploid cells for many mitotic divisions. |
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| Cytogenetic studies of mitotic and polytene chromosomes, allozyme data, and crossing studies indicate that An. dirus A and C are very closely related. |
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| This is most likely to be a problem for mutants with a mitotic phenotype. |
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| The assembly of a bipolar, microtubule-based machine called the mitotic spindle is essential for chromosome segregation during cell division. |
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| Supporting evidence for malignant transformation included high cellularity, increased mitotic activity, cellular pleomorphism, hemorrhage, and necrosis. |
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| The two poles of the mitotic spindle are occupied by centrosomes, which organize the microtubule arrays. |
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| In metaphase the condensed chromosomes align in a plane across the equator of the mitotic spindle. |
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| Tetrahymena divide by binary fission during vegetative growth, and the micronucleus and macronucleus are propagated by mitotic and amitotic division, respectively. |
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| This view is consistent with the general findings that mitotic recombination events, contrary to meiotic events, are mainly unassociated with crossing over. |
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| When skin is wounded, there is a burst of epidermal mitotic activity about 40 hours later. |
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| These tubules are made of the same protein as that in the mitotic spindle, the structure to which chromosomes are attached in cell division. |
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| However, the mitotic index is acceptable for suspension cultures in which other toxicity measurements may be cumbersome and impractical. |
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| This task is carried by a complex, multi-component machine, called the mitotic spindle. |
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| He studied the positioning of the mitotic spindle, an essential structure for all cell division. |
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| In particular, he investigated the functions and regulation of two mitotic kinases: Greatwall and Polo. |
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| Changes in the structure and ultrastructure of protoplasts during regeneration of the cell wall, mitotic cell division and amitotic nuclear fragmentation. |
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| A lack of pantothenate would result in slow growth, delayed septation, and mitotic defects. |
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| Inhibiting the formation of the mitotic spindle blocks cells from dividing. |
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| Polo regulates the mitotic functions and behavior of chromosomes and centrosomes, and the cytokinetic machinery by phosphorylating many crucial targets. |
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| The two centrosomes separate and move to opposite sides of the nuclear envelope, where each nucleates a starlike array of microtubules, forming the mitotic spindle. |
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| Griseofulvin exerts its antimicrobial activity by binding to microtubules, cellular structures responsible for forming mitotic spindles during cell division and for processing cell wall components needed for growth. |
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| The micronucleus undergoes two mitotic divisions to produce four micronuclei: two of these will form the new micronuclei of the cell, and two are destined to become the macronucleus. |
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| In prophase the mitotic spindle forms and the chromosomes condense. |
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| They are then transferred via the dendrites of the melanocytes to the keratinocytes of the mitotic layer of the epidermis which ingest them by phagocytosis. |
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| Cytotoxicity should be determined with and without metabolic activation in the main experiment using an appropriate indication of cell integrity and growth, such as degree of confluency, viable cell counts, or mitotic index. |
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| During asymmetric cell division, a balance of forces permits the mitotic spindle to move to one end of the cell in order to produce two cells of different sizes after division. |
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| Using this multi-disciplinary approach, he has made significant contribution to our current understanding of the mitotic kinesin motor Eg5, a key protein required for spindle assembly. |
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| This presentation concluded that Kip3D localizes to ends of mitotic spindle microtubules and is a microtubule depolymerizing kinesin. |
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| The depolymerizing effect of the colchicine solution on MTs was established using HeLa cells and flow cytometry to detect mitotic arrest. |
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| The kinetochore is a large multi-subunit and multi-copy protein complex that bridges mitotic chromosomes with spindle microtubules. |
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| The benign nature of this lesion was suggested by the lack of any mitotic activity, anaplasia, or dysplasia. |
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| Mechanisms for focusing mitotic spindle poles by minus end-directed motor proteins. |
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| There is increased spontaneous cancer in Tgfbi mouse knockouts, and knockdown of Tgfbi causes mitotic spindle abnormalities. |
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| Its role in mitosis of the embryo organizing the first mitotic spindle initiating the process of human development is now well established. |
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| The fibroblasts show pleomorphism, and apparent mitotic activity and a positive immunoreactivity with vimentin are seen. |
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| Many or the cells exhibited multinucleation, nuclear lobulation, and high mitotic activity. |
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| This mechanical connection is regulated by proteins of the mitotic checkpoint. |
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| Scattered multinucleate giant cells were present, as were numerous mitotic figures. |
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| They tend to be prominent, they are often hyperchromatic, and they frequently exhibit mitotic activity. |
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| She used mammalian cultured cells to investigate the mechanism of mitotic cell rounding in preparation for mitosis, a universal but poorly understood aspect of cortical dynamics in mitosis. |
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| In various coleopterans the mitotic and meiotic activities of the larval, pupal and imaginal stages occur diversely. |
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| On histologic analysis, unlike in leiomyosarcomas, the absence of mitotic figures, pleomorphism and hyperchromatism are the usual features. |
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| Positive results in the micronucleus test indicate that the substance induces micronuclei which are the result of chromosomal damage or damage to the mitotic apparatus in the erythroblasts of the test species. |
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| No drug-related increases in micronuclei were found. Hence, under the conditions used, the drug does not induce chromosome breaks or mitotic non-disjunctions in mouse bone marrow cells. |
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| In this study, mitotic gynogenesis and mitotic androgenesis were used. |
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| Just prior to cell division, chromosomes rapidly reorganize via unknown mechanisms and a specialized protein structure, the kinetochore, is constructed to mediate attachment to microtubules of the mitotic spindle. |
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| Microscopically, the tumor cells were arranged in diffuse compact trabeculae, with variable degrees of anaplasia, and increased mitotic activity in the control group. |
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| On microscopy, sections showed interlacing fascicles of spindled cells with diffuse pleomorphism, increased mitotic activity, and a focally infiltrative border. |
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| Lesions are made up of abundant vascular spaces and lobulated aggregates of closely packed capillaries lined by a flattened epithelium without anaplastic or mitotic features. |
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| Microscopic evaluation of mitotic activity is a routine procedure in assessing the grade of tumors, such as soft tissue sarcomas, meningiomas, or breast carcinomas. |
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| Artificial ones are recent, but natural ones include nuclei, mitochondria, mitotic bundles, the pores of channel protein, and other structures inside living cells. |
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| Dinoflagellate nuclei remain condensed throughout interphase rather than just during mitosis, which is closed and involves a uniquely extranuclear mitotic spindle. |
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| The target antigen is a 210-kDa centrophilin that is not only localized in the pericentrosomal region of mitotic cells but also present in interphase nuclear matrix. |
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| Prior to the current study, the known mitotic checkpoints monitored the proper completion of metaphase before allowing the process to proceed to anaphase. |
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| Neoplastic cells showed a high degree of anaplasia, high nucleus-to-cytoplasm ratio, usually one prominent nucleolus, partially condensed chromatin, and high mitotic index. |
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| Analysis of mosaic animals after mitotic recombination could permit to investigate the phenotype of the mutant clones in wild-type or otherwise mutant imaginal discs. |
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| This region included the Polo-like kinase 4 gene which is responsible for mitotic spindle formation, providing a likely explanation for the findings. |
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| When cells divide, Lis1 controls orientation of the mitotic spindle, an apparatus of subcellular fibers that segregates chromosomes during cell division. |
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| Cellular pleomorphism, mitotic figures, and necrosis are absent. |
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| Hematoxylin and eosin staining revealed no necrosis or mitotic figures. |
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| Necrosis, nuclear pleomorphism, and mitotic activity were not detected. |
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| Docetaxel, a microtubule stabilizing agent, has been reported to interfere with spindle microtubule dynamics causing mitotic cell cycle arrest and apoptosis. |
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| Toxicity to mitotic apparatus and karyotoxicity were also calculated. |
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| Histopathology demonstrated irregular lamellar bone with hypocellular fibrous stroma, but no obvious atypia, mitotic activity or necrosis mimicking fibrous dysplasia. |
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