This removal of apoptotic neutrophils by macrophage phagocytosis is a critical process for the resolution of inflammation. |
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Cells were incubated in the presence of phorbol ester myristate to induce macrophage differentiation. |
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Another potential mechanism involved in macrophage defense against M. tuberculosis is apoptosis or programmed cell death. |
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Alternately, it is possible that there is a defect in macrophage production in these animals. |
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Several drugs have been shown to derange macrophage functions, bactericidal efficacy and production and secretion of cytokines. |
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Once the bacterium is within the macrophage, the macrophage's bactericidal mechanisms destroy the microbe. |
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The role of macrophage apoptosis in containing the growth of the bacilli is also discussed. |
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Infection is cleared, usually within 2-3 weeks, by antibody opsonization and macrophage clearance. |
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Ceddia and Woods demonstrated that exhaustive exercise suppressed macrophage function for up to 24 hours post-exercise. |
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It is only the longer fibers which the macrophage can not fully engulf which if they are persistent can lead to disease. |
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Many mycobacterial species have co-opted as 'home' the very cell dispatched by the host to defeat them: the macrophage. |
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Use of a macrophage stimulating protein for the preparation of a medicament for use in stimulating thrombocyte production in a mammal. |
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However, when B. cepacia is engulfed, the macrophage does not fuse properly with the lysosome, and the bacteria are not digested. |
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Macrophages also are found in all tissues as wandering amoeboid cells, and the monocyte, a precursor of the macrophage, is found in the blood. |
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The other main type of scavenger cell is the macrophage, the mature form of the monocyte. |
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Zinc has been shown to inhibit some functions of polymorphonuclear leucocytes, to inhibit alveolar macrophage activity, and to facilitate pulmonary tissue injury. |
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They were also equally unable to opsonize fungal cells in a J774 macrophage phagocytosis and killing assay. |
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Weakened resistance to infection is caused by decreased antibody and complement production, leukocyte phagocytosis and intracellular killing, and macrophage phagocytosis. |
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Under conditions of CNS injury, another innate immune cell type, the macrophage, accesses the brain and spinal cord. |
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The dose of particles necessary to induce a reduction of macrophage phagocytosis was lower for SWCNT than for MWCNT and fullerenes. |
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How did opsonic antibodies enhance alveolar macrophage effectiveness? |
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The systemic immune effects include increased apoptosis of thymocytes, decreased macrophage phagocytosis, thymic atrophy and diminished allograft rejection. |
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If this does not kill the invader outright, then it acts as a flag for the bug in question to be eaten by a macrophage. |
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To this end, the set-up of a balanced regime in the biological samples was studied, both in macrophage cells and in biological tissue. |
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T cells are essential to the general regulation of immune response, Graft-versus-Host Disease and the proliferation of macrophage cells. |
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When associated with vesicles of dipalmitoylphosphatidylcholine, surfactant protein C inhibited the mitogenic effect of lipopolysaccharide to a macrophage cell line. |
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The number and viability of macrophage cells were assessed by trypan blue dye exclusion using a hematocytometer. |
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These modified toxins, or toxoids, usually are adsorbed onto an inorganic gel before being administered, an approach that increases the likelihood that the toxoid will be retained in a macrophage. |
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Modulation of macrophage functions by compounds isolated from Zingiber officinale. |
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Stressed Salmonellae produce MIPs soon after getting gobbled by a macrophage, Buchmeier and Heffron have discovered. |
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We hypothesized that low levels of neovascularization would be reflected in low macrophage counts. |
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This enzyme prevents a glycol protein found in blood serum from converting into Gc macrophage activating factor. |
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Induction of hypoferremia and modulation of macrophage iron metabolism by tumor necrosis factor. |
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When a monocyte enters the tissues it is called a macrophage. |
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In the first step in atherosclerosis, one type of white blood cell, the monocyte, takes up the modified LDL and accumulates cholesterol that can be converted into a macrophage foam cell. |
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Tremblay, Modulation of interferon-gamma-induced macrophage activation by phosphotyrosine phosphatases inhibition. |
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The green cell is infected with a poxvirus. It has been recognized as infected by a macrophage that is now trying to phagocytose, or eat, the infected cell. |
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Additional modes of action include alteration or inhibition of various enzyme systems, suppression of phagocytic activity of macrophage and polymorphonuclear leukocytes, and alteration of collagen biosynthesis. |
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The key white blood cell in inflammation is called a macrophage, and for decades it has been a subject of study in my hematology laboratory and in many others. |
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But macrophage signalling also involves SNAP-25, so Dr Chapman thinks he can use botulinum toxin to shut the cells up. The problem is that macrophages have no synaptotagmin on their surfaces. |
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Eventually, the macrophage dies and bursts open, releasing large numbers of bacteria into the lungs and thus repeating the cycle of macrophage ingestion and bacterial replication. |
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At the time of Steinman's discovery, a type of immune cell known as the macrophage and the other major type of white blood cell, the B cell, were thought to be the primary antigen-presenting cells in mammals. |
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In addition, the uptake of LDLs initiates an inflammatory response that increases macrophage presence and, over time, results in coronary artery disease. |
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Grape powder polyphenols attenuate atherosclerosis development in apolipoprotein E deficient mice and reduce macrophage atherogenicity. |
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The second part of Collman's presentation concentrated on inappropriate macrophage activation in HIV pathogenesis. |
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Absence of a classically activated macrophage cytokine signature in peripheral spondylarthritis, including psoriatic arthritis. |
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Modulation of nitric oxide, hydrogen peroxide and cytokine production in a clonal macrophage model by the trichothecene vomitoxin. |
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Immune modulation of macrophage pro-inflammatory response by goldenseal and astragalus extracts. |
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The subunits then assemble into the active ring-form on the membrane of a polymorphonuclear leukocyte or macrophage. |
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Indeed, Type I IFNs have been shown to inhibit macrophage activation, thus discouraging mycobactericidal activities during Th1 immunity. |
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Metal transporters, NRMP-2 and DMT-1 transport the recovered iron through the phagosomal membrane to the cytoplasm to be stored in the macrophage bound to ferritin. |
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Fetuin opsonizes cationic macrophage deactivating molecules. |
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On the other hand, osteopontin is a large phosphoglycoprotein adhesion molecule with pleiotropic effects that include promotion of macrophage accumulation. |
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In addition, in this survey, the inhibition of infection in macrophages and cytotoxicity effects of both the extracts on murine macrophage cells were investigated. |
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Evidence for toxicity of phlogopite in hemolysis and macrophage tests. |
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Macrophage cells secrete chemicals that can dissolve bone under an implant. |
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Macrophage cytotoxicity against schistosomula of schistosoma mansoni involves arginine-dependent production of reactive nitrogen intermediates. |
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