| When an enzyme is not working, it leads to the build up of the sugar chains in the lysosome. |
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| However, when B. cepacia is engulfed, the macrophage does not fuse properly with the lysosome, and the bacteria are not digested. |
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| The remaining debris generally stays within the lysosome and is called a residual body. |
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| Each enzyme in the lysosome is responsible for a certain step in the breakdown of the sugar chains. |
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| In a lysosomal disease, for some genetic reason, the lysosome does not carry out its function. |
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| For example, the internal space of lysosomes is much more acidic than that of the cytosol pH 5 as opposed to pH 7 and is maintained by specific proton-pumping transport proteins in the lysosome membrane. |
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| This critical modification allows the enzymes to bind to specific receptors on the membrane of the Golgi, which then directs them into vesicles leading to a lysosome rather than a secretory vesicle. |
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| The site of action for idursulfase is the lysosome, and so the observed reductions in GAG levels were therefore considered to be indicative of lysosomal uptake of idursulfase. |
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| Lysosomal diseases are rare genetic diseases which include about fifty handicapping affections of the child and the adult. Their common feature is a genetic deficiency inducing a malfunction of the lysosome. |
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| To devour a mitochondrion, a cell first swaddles it in a shroudlike membrane, which is then transported to a lysosome. |
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| During the process, nutrients are recycled by the lysosome, an internal organelle, to produce metabolites that can be used by the cell. |
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| To ensure this only happens at the fingerprints, molecules are attached to the nanoparticles that bind to lysosome, which is found in human sweat and left in fingerprint residue. |
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| These conditions are called lysosomal disorders after the lysosome, the structure in the cell that contains these substances, and often produce symptoms of neurological involvement at birth or in the early years of childhood. |
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| Permeases in the lysosomal membrane, for example, allow amino acids generated inside the lysosome to cross into the cytoplasm, where they can be used for the synthesis of new proteins. |
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| A lysosome is part of the structure of a cell and is responsible for breaking down certain types of substances so that they can be discarded or reused by the body. |
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| Egg white is a natural biomaterial that contains high amount of amino acids and various proteins such as albumin and lysosome. |
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| Instead of being lysed by lysosomes the virus' outer coat merges with the lysosome membrane and releases the capsid, which will then disintegrate within the cytoplasm. |
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| He also noticed a close association of the Golgi body, endoplasmic reticulum and lysosomes, a hybrid structure he called GERL, which helped clarify lysosome biogenesis. |
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| Autophagy is the process by which waste is taken to a cell's lysosome. |
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