How to use inhibition in a sentence

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Sentence Examples Blood vessel dilation is due to blockage of calcium channels in smooth muscle cells or inhibition of sodium-calcium ion exchange. The addictive and euphorogenic effects of cocaine are thought to result primarily from inhibition of dopamine reuptake. The antibacterial activity appears to be the result of mitochondrial respiratory chain inhibition. For example, often there is cortical inhibition, as evidenced by very slow EEG theta waves. One example is the antihypertensive effect of dietary peptides derived from milk protein, mediated by angiotensin converting enzyme inhibition. This loss occurs because of quadricep inhibition, which then leads to muscle atrophy. The main characteristic of whole body withdrawal is complete inhibition of swimming. Lateral inhibition is also involved in the regular spacing of hair cells or trichomes on root and leaf surfaces. The emergent event is an unexpected disruption of continuity, an inhibition of passage. The effect of the subpoena did not result in an unconstitutional inhibition of religion. This reduction reflected the shunting and reduced amplitude of the antidromic action potential by the inhibition. One of the principal mechanisms of the anticarcinogenic activity of tea is inhibition of the initiation stage of carcinogenesis. Antiviral properties of the plant extracts were determined by cytopathic effect inhibition assay and virus yield reduction assay. The final and ultimate breakthrough took place, and he was able to teach and work with sentient beings without any inhibition. Similar calmodulin-mediated phosphorylations lead to inhibition of glycogen synthase. Clearly the formal setting was no inhibition to the rough and tumble of family life. As a personal poet, he attacked enemies by name and described without inhibition his own amatory exploits. Insertion of the same number of extra molecules into distal monolayers did not result in any inhibition of bilayer fusion. With inhibition or failure of the skin's protective mechanisms, cutaneous infection may occur. A characteristic feature of the cellular response to ionizing radiation exposure is inhibition of replicon initiation. Show More Sentences The inhibition of proteinases by protein proteinase inhibitors is an individual case of protein-protein interaction. As a result of this hormonal inhibition, your body stores fat and holds on to it stubbornly. Even if short-term inhibition of GDP growth is on occasions necessary, growth foregone is nevertheless the very essence of social misfortune. High levels of cortisol contribute to lower levels of testosterone and inhibition of dominant or territorial behaviors. This inhibition is to a large extent based on the Bill of Rights and the consequent bar to the impeachment of proceedings in Parliament. Classically, diagnosis of dengue virus infection was carried out by haemagglutination inhibition test. But until they slough off that inhibition they will fight the opposition with one hand tied behind their back. Gamma-tocopherol partially protects insulin-secreting cells against functional inhibition by nitric oxide. The moral that Freud drew from this reasoning was that the inhibition of natural emotional expressions could lead to dangerous consequences. The orectic response to energy expenditure and the orectic inhibition to fat accumulation are feedback mechanisms which are impaired in obesity. These results suggest that inhibition of p70 S6K is not causatively related to the apoptotic response. The spindle is thought to be responsible for the inhibition of external, sensory input. Note from the text of the full paper that stress causes the release of the hormone corticosterone which lowers latent inhibition. In particular, they found that measures of working memory, attentional capacity and inhibition overlapped with measures of executive function. She then builds up a secondary inhibition to sexual arousal in order to avoid the frustration accompanying an unsatisfying sexual experience. Much evidence suggests the presence of tonic neurogenic inhibition in the colon. There was also an improvement in cell-mediated immune status, as assessed by the leukocyte migration inhibition test. Fluorouracil induces apoptosis by inhibition of the enzyme thymidylate synthase during DNA replication. An imbalance of excitation and inhibition may underlie several neurological diseases, including autism, Tourette's syndrome and schizophrenia. In contrast, PKC inhibition did not suppress the growth of normal mast cells. Show More Sentences Moreover, inhibition of the cysteine protease activity by chemical inhibitors suppressed the leaf senescence process. On the other hand, the present findings do support the proposed multidimensional nature of behavioral inhibition. The inhibition of pathogenic bacteria by probiotics is an orchestrated combination of structure and function. In cases of severe growth inhibition, the wings appeared crumpled with strong structural deformation. It may involve simultaneous activation of some belief representations and inhibition of others. Although the specific locus of task-set inhibition is not yet clear from the available evidence, three possibilities can be ruled out. The addition of scavengers suggests that reactive oxygen species caused this bacterial growth inhibition. What was more, I was determined to defy the frigidity of my race, that ancient shameful legacy of inhibition. Both assays have an amplification control that will indicate inhibition to prevent reporting false negatives. Similar dose-dependent inhibition was also observed in the time-course experiments using vanadate and azide. The beneficial actions of hypercapnic acidosis were not mediated by inhibition of nitration of amino acid residues within proteins. Furthermore, the model postulates that individuals vary in their propensity for both excitation and inhibition. Children completed a battery of neuropsychological tests in the areas of processing speed, vigilance, and inhibition. The resulting synaptic inhibition is characterized by either a depressant or an excitant effect, depending on the population of cells involved. Small amounts of eserine result in inhibition of choline-esterase without manifestation of physiological effects. Carbosulfan is extremely toxic to mammals and its toxicity is mediated through inhibition of acetylcholine esterase, a respiratory enzyme. Enzyme inhibition prevents the formation of thromboxane A 2 from arachidonic acid. At all levels, but particularly at the mid-collicular and pontine levels, there was a pronounced inhibition of eupnea by sighing respiration. Within skeletal muscle and heart activation of AMPK leads to the phosphorylation and inhibition of acetyl-CoA carboxylase. For irradiation, cells were cultured in Petri dishes and synchronized by contact inhibition in confluent cultures. Show More Sentences I sense in Monica's response a surprising inhibition, a lack of confidence that a true union is possible. Its anti-inflammatory effects are possibly from its inhibitory action on the arachidonic acid pathway via cyclo-oxygenase inhibition. It has been reported that the use of THH leads to reversible inhibition of germinal cell development in both humans and rats. The management of depression has advanced greatly with the development of antidepressant agents based on neurotransmitter reuptake inhibition. A study on the effects of acute dopamine reuptake inhibition on performance. Interestingly, they report wind-rose plots indicating that MLCK inhibition substantially reduces cell motility by increasing the directional tortuosity of cell paths. His style is quite bluesy and completely without inhibition. This occurs at chemical synapses when neurotransmitters are released from the presynaptic neuron and produce excitation or inhibition of the postsynaptic cell. This inhibition was observed in both the directly and indirectly stimulated contractions, and was not changed by addition of neostigmine, an acetylcholine esterase inhibitor. Methionine synthase inhibition causes folate trapping and a reduction in the amount of folate available for thymidine synthesis as described above. Confused with the orders of Judge Vianzon, respondents filed a manifestation seeking clarification whether the judge had recalled his earlier order of inhibition. Several nucleoside-based inhibitors of these viral enzymes, including that of the HIV virus, also typically show modest inhibition of telomere synthesis. Despite inhibition of viral replication in plasma, lymph nodes, and at other sites, reservoirs of HIV infection in latently infected resting T lymphocytes remain. Indeed, the very nature of the inhibition remains the focus of debate, and various attentional, motoric, and perceptual explanations have been proposed. There is no reason to think other large single-currency areas, such as China, pay any smaller cost in terms of overall GDP inhibition and regional disparity. Cocaine blocks the initiation or conduction of nerve impulses following local application by blocking depolarization via sodium influx inhibition. The three main laboratory methods used to screen newborns for PKU are the Guthrie bacterial inhibition assay, fluorometric analysis and tandem mass spectrometry. Measurements of the fluorescence of dansyl cadaverine attached to Gln 41 indicate substantial inhibition of the initial association of G-actin-S1 into longitudinal dimers. This process can lead to the addition or inhibition of cellular function. So, by such a transport inhibition of ketone body efflux from the liver, the brain is deprived of those energetic compounds leading to lower BDH activity. Show More Sentences Both fluorescent proteins are genetically encodable, their emission spectra are well separated and mRFP1 is monomeric, reducing the possibility of protein function inhibition. Such variations might arise from minor genetic differences or by epigenetic influences causing induction, enhancement or inhibition of repair enzyme synthesis or activity. Flavonoids have diverse toxic effects including disruption of cellular respiration, inhibition of enzyme function, and interference with reproduction. This issue is related to the inhibition of carrier relaxation due to the selection rule of interaction between electrons and phonons in discrete energy level systems. The nematocidal drug ivermectin is believed to kill worms by opening a glutamate-gated chloride channel on pharyngeal muscle, causing complete pumping inhibition. However, disconformity of practice with constitutional requirements is no inhibition against truly expounding the text and implications of the Constitution. Alterations in serotonin levels, enhanced glutamate release, or inhibition of neurogenesis may be important factors in the central nervous system effects of corticosteroids. The expression of the lordosis posture is under tonic inhibition by brain nuclei whose activity is suppressed by steroid hormones from the preovulatory follicles. In cells recovering from the inhibition of actin polymerization by latrunculin A, the assembly of actin filaments is dissociated from its linkage to membrane protrusion. The tropic response represents a growth response to altered auxin levels, involving growth stimulation and growth inhibition on opposite sides of the responding organ. With respect to this subject, the reported DNA damage and inhibition of DNA repair functions by photooxidative reactions is an interesting aspect. Their specificity could be related to particular defined groups on the antigen and evaluated quantitatively with precipitin reactions and hapten inhibition of precipitation. Her ADHD subjects were particularly masterful when the talent in question involved a lack of inhibition. The alternative possibility, that the kinetic complexity of Mg-G-actin digestions arises from trypsin inhibition in these reactions, has been tested in two ways. The brain consists of millions of interconnected neurons, and cognitive activity reduces, ultimately, to patterns of neuronal excitation and inhibition. To characterize the mode of inhibition, they analyzed whether binding of eiseniapore to membranes and lytic activity were affected by these substances. Yes, but the practical effect of the inhibition on the lawyer to give a communication is to inhibit the receipt of the communication by the person to whom it is directed. Hanging can trigger a reflex known as vagal inhibition, which can instantly stop the heart. We have investigated the possibility that the inhibition of the blastogenesis responses may be due to a modulatory effect of an acute phase protein. The kidneys secrete more urine, not only because of the fluid drunk but also because of the osmotic effect of alcohol and inhibition of secretion of antidiuretic hormone. Show More Sentences Besides the aforementioned carbohydrates, we also observed inhibition of the hemagglutination when we incubated the lectins with fucose. We investigated apoptozole as a potential chemical tool for HSP70 inhibition. This could be due to an inhibition in the underlying mechanism, or it could just mean that some shorter polarity intervals have been missed. Tanshinone IIA induces autophagic cell death via activation of AMPK and ERK and inhibition of mTOR and p70 S6K in KBM-5 leukemia cells. Metalloproteinase inhibition ameliorates hypertension and prevents vascular dysfunction and remodeling in renovascular hypertensive rats. Hyaluronidase inhibition assay was studied in vitro using bovine testicular hyaluronidase and human umbilical cord hyaluronic acid. Tumor necrosis factor-induced c-myc expression in the absence of mitogenesis is associated with inhibition of adipocyte differentiation. Can the relative contributions of ADCC and target inhibition toward tumor shrinkage be quantified? Divalent cation inhibition of hormone release from isolated adenohypophysial secretory granules. In this work we used mass loss method and thermometric measurement to calculate the corrosion inhibition efficiency. In a rat study, sodium fluoride produced concentration-dependent inhibition of leptin secretion. Durability of the binding inhibition of albumin coating on tympanostomy tubes. Release of prostaglandins E and F in an algogenic reaction and its inhibition. Similarly, opiate withdrawal-related LC hyperactivity could be turned off by clonidine, and that inhibition reversed by yohimbine or piperoxane. Moreover, PQQ protected cells from mitochondrial inhibition by rotenone, 3-nitropropionic acid, antimycin A, and sodium azide. This is substantiated if a paper disc with polyvalent H antiserum has been included on the plate, and a zone of inhibition can be seen around it. The composition provides an inhibition of bacterial adhesion to an apatite test plate analyzed by scanning electron microscopy. Vitex has dopaminergic activity associated with the inhibition of prolactin synthesis and release in hyperprolactinaemia. Through inhibition of the cyclooxygenase pathway of arachidonate metabolism, NSAIDs prevent the production of the proinflammatory prostaglandins. The HIV protease inhibitor project is targeted at inhibition of the HIV protease enzyme and is in the pre-clinical research phase. Show More Sentences The response in percentage was calculated to evaluate the toxicity of xenobiotics via the inhibition of cell growth of protists. Noncompetitive functional inhibition at diverse, human nicotinic acetylcholine receptor subtypes by bupropion, phencyclidine, and ibogaine. But biologic treatments such as angiogenesis inhibition, viral oncolysis, and gene therapy are more promising in the long term. Hyposexual desire may result from hypofunctional excitation, hyperfunctional inhibition, or some mix of the two. In vitro inhibition of drug-resistant and drug-sensitive strains of Mycobacterium tuberculosis by ethnobotanically selected South African plants. The researchers speculate that MAO A inhibition may explain and reinforce the ethnomedical claims of the antidepressant effect of Rhodiola. Selective inhibition of mitochondrial respiration and glycolysis in human leukaemic leucocytes by methylglyoxal. Dr Arnall of Cardiff University said, 'For most people going on roller coasters is a way of losing inhibition. Extraverts in comparison to introverts have less cortical arousal and more mental reactive inhibition. He said she could have died from vagal inhibition due to pressure on her neck which would have shut down the whole of her nervous system. Urease inhibition activity was determined by measuring ammonia production using the indophenol method as described by Weatherburn. Compound 4 showed better or comparable cyclooxygenase enzyme inhibition than positive controls. Tyrosinase inhibition by extracts and constituents of Sideroxylon inerrne L stem bark, used in South Africa for skin lightening. This condition is a result of absent subthalamic nucleus inhibition, which increases motor activity through the motor thalamus. Recurrent inhibition of flexor muscles motoneurons of the man forearm research under vibration and static muscle straininfluence. The inhibition of phenylhydroquinone-induced oxidative DNA cleavage by constituents of moutan cortex and paeoniae radix. Previously, researchers had hypothesized that the inhibition of checkpoints enhanced the effects of DNA-damaging chemotherapy on cancer cells. Interneurons integrate into the brain and provide controlled inhibition to balance the activity of nerve circuits. Contact inhibition is the impediment of excessive growth of cells by neighboring cells. In vitro inhibition of cyclooxygenase and 5-lipoxygenase by alkamides from Echinacea and Achillea species. Show More Sentences Carbodiimide chemistry research interest focused as a tool to aid nucleotide and peptide synthesis and as permease inhibition. They showed that vibration disinhibits the recurrent inhibition of Renshaw cells. More specifically, inhibition of their activity disinhibits the activity of the prefrontal projection neurons, and synchronises their action. Simultaneous isolation, amplification, and detection of a standard amount of phocid herpesvirus were used for internal control of inhibition. To monitor the quality of DNA extraction and potential PCR inhibition, we added low concentrations of phocine herpesvirus to the lysis buffer. Tremblay, Modulation of interferon-gamma-induced macrophage activation by phosphotyrosine phosphatases inhibition. The reduction of eicosanoid release was related to the inhibition of cyclooxygenase-2 expression. The RNA eluate is readily suitable for direct lysate RT-PCR with no inhibition. In vivo inhibition of foam cell development by probucol in Watanabe rabbits. A bacterial substance known as indoleacetic acid may play a part in sprout inhibition. The fungitoxic effects of fungicide resulted in inhibition of Trichoderma isolates tested in this investigation. All the selected dihydroxyflavone derivatives showed dose and time dependent inhibition of carrageenan induced paw oedema. Corrosion inhibition of aluminium in acidic and alkaline media by Sansevieria trifasciata extract. Two different concepts, attentional inhibition and attentional monitoring, are used to measure attentional control. Reversible inhibition of photophosphorylation in chloroplasts by nitric oxide. The growth inhibition caused by viral infection can cause substantial economic damage. A random reversal pattern with inhibition can be represented by a gamma process. The rainfall inhibition and the dissipation of cloud cover are most accentuated over the eastern section of the Sahara rather than the western. This inhibition of the arcuate nucleus is an ongoing active suppression by other areas of the brain. The detailed mechanism of these chemical compounds range from inhibiting growth of the bacteria to the inhibition of specific enzymes. Show More Sentences Hyperkalemia in azotemic patients during angiotensin-converting enzyme inhibition and aldosterone reduction with captopril. Bradycardia and hypotension occur due to inhibition of nor-adrenaline secretion and increased reflex baroreceptor activity. Effect of angiotensin converting enzyme inhibition on blood pressure and renal function during open heart surgery. In vivo inhibition of acetylcholinesterase and aliesterases by the five compounds was determined for both species. Results of and further prevention of hypoxic fetal brain damage by inhibition of xanthine oxidase enzyme with allopurinol. The role of enzyme and substrate concentration in the evaluation of serum angiotensin converting enzyme inhibition by enalaprilat in vitro. The graph above the zymogram shows the lack of inhibition of proliferation at this time point. The signal and mechanism releasing the arcuate nucleus from inhibition have been the subject of investigation for decades and remain incompletely understood. We recently reported on a novel mechanism of chemoprotection by SFN in human colon cancer cells and prostate epithelial cells, namely the inhibition of histone deacetylase. Like other sympathomimetics, synthetic cathinones appear to stimulate the central nervous system via inhibition of norepinephrine and dopamine reuptake mechanisms. Nucleosides from the media may be transported across the cell membrane compenstating for the antifolate inhibition of biosynthesis of these nucleotide precursors. The mechanisms of action may include the antinociceptive effect of melatonin involving the activation of supraspinal sites and the inhibition of spinal windup. The primary outcome was the inhibition of worsening cartilage damage in both knees, as assessed using detailed MRI examination of 14 articular subregions in each joint. But the child is shamed and punished for exhibiting that shadow, so he introjects the parental judgments and develops another behavior set, that of self-blame and inhibition. Moreover, more and more evidence is evolving that inhibition of entry and intrahepatic spread of HBV and HDV may play an essential role of future curative regimes. The authors demonstrated the inhibition of the interaction in yeast 2 hybrid and mammalian 2 hybrid screens and showed anti-HIV activity in the micromole range. It can be said that the positive evolution of the response percentages confirm the growth inhibition of the treated paramecia and this regardless of the cell concentration. They hypothesized that reports of greater insomnia severity would be associated with lower pain thresholds and inhibition and with greater temporal summation of pain. In addition, in this survey, the inhibition of infection in macrophages and cytotoxicity effects of both the extracts on murine macrophage cells were investigated. The group given saccharin preexposure without any swim stress exhibited a typical latent inhibition effect in which the conditioned response was relatively poor. Show More Sentences Agetect has proven collagenase and hyaluronidase inhibition activity. Is it not possible that dopamine inhibition in the mesolimbic system might hypersensitize that tract to manifest psychotic symptoms when that inhibition is lifted? According to the researchers, the Yop M-mediated inhibition of caspase-1 is required for Yersinia to subvert immune signaling, delay inflammation and provoke severe illness. Aim of this study was to test the monoamine oxidase inhibition activity of the same AFA extract and of its constituents phycocyanin and mycosporine-like aminoacids. Taken together, our results show that SA has a potent antiadipogenic effect in 3T3-L1 cells due to the inhibition of adipocyte differentiation and adipogenesis. The inhibition of tyrosinase can play a key role in the management of diseases such as cutaneous hyperpigmentation disorders such as lentigines, and possibly melanoma. Normalization of dehydroepiandrostenedione sulfate and elevation of progesterone suggest inhibition of 17-hydroxylase and 21-hydroxylase activities by sorafenib. In the presence of digoxin the system I produces membrane sodium potassium ATPase inhibition of archaeal membrane and a paroxysmal depolarisation shift. Similarly, ABCG2 and SLC22A1 inhibition by fumitremorgin C and amantadine, respectively, did not result in any significant difference in intracellular bosutinib levels. In mouse erythroleukemia and fibroblast cells, inhibition of fos and jun has demonstrated their requirement for proliferation and cell-cycle progression. Passive transfer of antibodies protects immunocompetent and immunodeficient mice against lethal Ebola virus infection without complete inhibition of viral replication. Importantly, inhibition of NOX by apocynin significantly protected against PCB-mediated increase in epithelial permeability and alterations of ZO-1 protein expression. In a preclinical model of efficacy, PRS-080 administration showed complete inhibition of hepcidin-induced hypoferremia in a dose-dependent manner. Phosphorylation of focal adhesion vasodilator-stimulated phosphoprotein at Seri57 in intact human platelets correlates with fibrinogen receptor inhibition. Bumetanide inhibition of the blood-brain barrier Na-K-Cl cotransporter reduces edema formation in the rat middle cerebral artery occlusion model of stroke. Our data suggest that inhibition of NEDDylation may be a useful strategy to resensitise tumour cells in patients that have acquired carboplatin resistance. Aprotinin exhibited nearly stoichiometric inhibition of prostasin and matriptase, but was much weaker towards HAT and was completely ineffective versus tryptase. It reduces melanogenesis through a mechanism blocking the melanin release by the melanocytes, an alternative to the broadly known inhibition of tyrosinase. Remarkably, local intra-fat Y2R inhibition pharmacologically or via adenoviral Y2R knock-down reverses or prevents fat accumulation and metabolic complications. The electromagnetic induction of membrane sodium potassium ATPase inhibition mediated ATP synthesis may also be a similar primitive source of cellular energy. Show More Sentences It has a unique profile with two mechanisms of action, combining mu-opioid receptor agonism and noradrenaline reuptake inhibition properties in a single molecule. Examples from Classical Literature Without inhibition there is no instigation of imagination, no redirection into more discriminated and comprehensive activities. Logical conduct is, then, conduct which aims to remove ambiguity and inhibition in unreflective conduct. We saw that in every act of attention the process of inhibition is essential. It produces death by inhibition of the hearts action, and by paralyzing the pneumogastric nerve. If you can once overcome an inhibition, you have broken its hold. The altered morphology occurred within 24 hours of treatment with GRN163L and was independent of telomerase inhibition or telomere length. The electrical discharges induced by digoxin induced sodium potassium ATPase inhibition can generate a plasma state of matter within the cell. The professor claims that death is due to a phenomenon of inhibition. It is known that aldicarb can cause inhibition of cholinesterase, a well-known biomarker of exposure. I think their inhibition comes by means of the late innovation. Peer-reviewed data from the Fox Chase Cancer Center suggest that talabostat, a high affinity inhibitor of FAP, can suppress tumor growth via FAP inhibition in mouse models. The first generation of MAO inhibitors was characterized by a lack of selectivity in their MAO inhibition, inhibiting both MAO-A and MAO-B with serious side-effects. Color-Word Reading is the third component of the Stroop test, which is a measure of response inhibition requiring patients to inhibit a prepotent response. It was not reason on his part, but inhibition which had become habit. Find more words! 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What is the opposite of inhibition? Words that rhyme with inhibition What is the plural of inhibition? What is the adverb for inhibition? What is the adjective for inhibition? What is the noun for inhibition? Translations for inhibition Use our Sentence Generator Nearby Words inhibiting inhibited inhibit inhesion inherits inheritors inhibitions inhibitive inhibitor inhibitors inhibitory inhibits 10-letter Words Starting With i in inh inhi inhib inhibi inhibit inhibiti inhibitio