| Trials have demonstrated threshold dose effects for two of the most active chemotherapeutic agents, doxorubicin and cyclophosphamide. |
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| He received treatment with multiagent chemotherapy that consisted of vincristine, doxorubicin, cyclophosphamide, and prednisone. |
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| Most standard protocols use doxorubicin and cisplatin, with or without high-dose methotrexate, for both induction and adjuvant chemotherapy. |
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| Human lung-cancer cells were treated with the chemotherapeutic agent doxorubicin, which causes cellular DNA damage. |
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| She was treated with cyclophosphamide, doxorubicin, vincristine, and prednisone and had a good initial response. |
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| Cancer drugs used for primary bone cancer include methotrexate, doxorubicin, and cisplatin. |
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| Chemotherapy usually consists of a combination of agents, such as hexamethylmelamine, doxorubicin, cisplatin, carboplatin, and paclitaxel. |
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| Leukemia lines resistant to either doxorubicin, vincristine, methotrexate, or hydroxyurea were tested. |
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| Adjuvant therapy, multidrug chemotherapy was carried out with methotrexate, cyclophosphamide, doxorubicin, vincristine, and prednisone. |
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| Cytotoxic antibiotics, such as doxorubicin, stick to DNA causing it to become tangled and preventing the cell from dividing. |
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| She underwent 6 cycles of cyclophosphamide, doxorubicin, vincristine sulfate, and prednisone chemotherapy and obtained remission. |
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| The patient is currently undergoing further evaluation for chemotherapy with cyclophosphamide, vincristine, doxorubicin and prednisone. |
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| The patient completed 4 cycles of combination chemotherapy consisting of cyclophosphamide, doxorubicin, vincristine sulfate, and prednisone. |
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| Combined chemotherapy, including cyclophosphamide, vincristine, doxorubicin, and prednisolone, was performed on the basis of clinical diagnosis as a lymphoma relapse. |
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| For the study, 101 participants were treated with doxorubicin alone. |
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| She was then placed on an investigational chemotherapeutic protocol, which involved a nine course of sequential high dose doxorubicin and cyclophosphamide. |
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| Prostate cancer cells were treated with silibinin and doxorubicin, either alone or in combination, and cell growth was determined by manual cell counting. |
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| The patient was started on chemotherapy with cyclophosphamide, doxorubicin, and dacarbazine administered as a continuous 7-day infusion, repeating every 21 days. |
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| It has been reported that doxorubicin can be concentrated to such an extent within liposomes that gelation takes place in the presence of the divalent sulfate counterion. |
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| The chemical was an experimental derivative of a well-established anti-cancer drug called doxorubicin. |
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| The Company has established a proof-of-concept with doxorubicin, a cytotoxic drug, showing its efficient delivery in animal solid tumor models. |
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| This patient had other potential risk factors including substantial exposure to doxorubicin and concomitant cyclophosphamide. |
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| When TAXOL is used in combination with doxorubicin for treatment of metastatic breast cancer, monitoring of cardiac function is recommended. |
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| Dr Hammond has picked one that does this to the protein of which the pumps are made. The bomb's inner layer, its payload, is made of a standard chemotherapy drug, doxorubicin. |
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| In vitro studies on human and murine anthracycline-resistant cells have revealed a lower degree of cross resistance for idarubicin in comparison with doxorubicin and daunorubicin. |
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| Data from different animal species and in vitro models have shown that epirubicin is less toxic, and in particular less cardiotoxic than doxorubicin. |
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| An additional study, P071, was conducted in patients receiving moderately emetogenic chemotherapy including cyclophosphamide and possibly doxorubicin or epirubicin. |
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| The others were, respectively, capsules of hyaluronic acid loaded with siRNA alone, similar capsules loaded with doxorubicin and an inactive control RNA, and the full combination of hyaluronic acid, siRNA and doxorubicin. |
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| The theory is thus that the hyaluronic acid will guide the bomb to its target, the siRNA will disable its defences and the doxorubicin will blow it up. |
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| Dr. Holland said Mr. Lautenberg would receive the standard chemotherapy regimen for his cancer, known as R-CHOP, a combination of rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone. |
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| A DNA having the configuration of restriction sites shown in Figure 1 or 2 of the accompanying drawings or a restriction fragment derived therefrom containing a gene coding for doxorubicin resistance. |
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| Hypoxia induced resistance to doxorubicin in prostate cancer cells is inhibited by low concentrations of glyceryl trinitrate. |
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| Streptozocin in conjunction with doxorubicin or 5-flurouracil is approved for pancreatic NET, but is limited by its toxicity profile. |
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| Super-Leu-Dox consists of doxorubicin conjugated to a proprietary prodrug peptide. |
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| Formerly, the combination of vincristine, doxorubicin, and dexamethasone was commonly used, but is being replaced by nonchemotherapy options. |
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| Mice were injected intratibially with mouse OS cells and then randomized to receive placebo or doxorubicin. |
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| Combination treatment with streptozocin and doxorubicin is the favored first-line therapy in advanced disease. |
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| The widely used antineoplastic drug, doxorubicin produces a dose-related cardiomyopathy as a serious side effect, which makes its clinical utility limited. |
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| The other drugs were doxorubicin, cisplatin, methotrexate and vincristine. |
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| Doxorubicin hydrochloride and daunorubicin hydrochloride are 2 drugs which compose a larger class known as anthracyclines. |
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| Doxorubicin lowers left ventricular ejection fraction, and some patients develop heart failure as a result. |
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