How to use de novo in a sentence

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Sentence Examples So, a strong case exists for substantial de novo protein synthesis in anoxic rice coleoptiles. Toe and cleft ulceration developed de novo in patients treated with four layer compression bandaging for venous ulceration. Our analyses also suggest that the utilization of products of de novo pyrimidine biosynthesis may differ between different cell types. Constitutive proteolysis, however, is the main source of free amino acids used for de novo protein synthesis. Fibrosarcoma of the ovary is a rare tumor that is considered to arise de novo or secondary to benign fibromatous tumors. The de novo assembly of silent chromatin requires passage through the S phase of the cell cycle. The first type, which arises de novo in adults, is characterized by myocarditis, myositis, lymphadenitis, hepatitis, and chorioretinitis. The first of these three issues was not pursued because the constitutional challenges were argued de novo in the context of the second issue. The physiological characterization of transgenic plants suggested that betaine might accelerate protein synthesis de novo during recovery from stress. Consequently they concluded that habitual residence was a legal determination and could be subject to de novo review. Continue to pursue merger and acquisition opportunities, de novo branch expansion, new product offerings and expanded channel capabilities. Indeed, all the genes encoding enzymes required for de novo AMP biosynthesis are repressed at the transcriptional level by the presence of extracellular purines. It is also possible that the first-group enzymes play important roles in the de novo synthesis of glucan primers and the initiation of starch granules in the endosperm. Truly non-Mendelian inheritance, e.g. de novo events can be masked as well. In a similar fashion, the final stage of animal cytokinesis is based on de novo formation of the plasma membrane via the interdigitating microtubules known as the midbody. The text also provides that the duration could be extended if it would be desirable to extend the system, rather than setting it up de novo. This appeal is not de novo, meaning that only the evidence examined by the citizenship judge is admissible in court. Discretion to allow or not to allow for the record to be supplemented is incompatible with the notion of a de novo review. Such barriers are sufficiently high as to make de novo entry an expensive strategy with a high risk of failure. Studies in simian cell lines transfected with human alpha satellite sequences showed that these repetitive regions could form de novo centromeres on existing chromosomes. Show More Sentences Both the Federal Reserve and the Office of the Comptroller of the Currency recommend that Congress remove outdated barriers to de novo interstate branching. The day is not far away when enzymologists will astonish us all by creating more or less de novo enzymes endowed with hitherto-unknown catalytic properties. The translocation was found to be de novo as the parental karyotypes were normal. Frequent de novo moncallelic expression of R-spectrin gene in children with hereditary spherocytosis and isolated spectrin deficiency. The Court must examine whether the discretion was exercised in good faith, rather than conduct a de novo review of the exercise of the discretion. The Court found that s. 7 of the Charter does not guarantee a second hearing de novo at the IRB to individuals who have obtained refugee status by fraudulent means. Overexpressing centriole-replication proteins in vivo induces centriole overduplication and de novo formation. The technique of chemically assisted fragmentation was used to obtain de novo amino acid sequence data from tryptic peptides. So we didn't start de novo, we developed from self-regulation. Certainly, a de novo system would recognize that Prince Edward Island or Manitoba would not have the population mass needed to support specialized services, such as pediatric cardiac surgery. Glycogen storage capacity and de novo lipogenesis during massive carbohydrate overfeeding in man. The de novo appeal ensures that applicants have an opportunity to present their case in person if there is a serious possibility that their application may be denied. Did gemmiferous shoots evolve de novo in the huperzioid lineage, or were they modified from shoots of an anisodichotomously branching ancestor? Protein binding protects sites on stable episomes and in the chromosome from de novo methylation. Suburethral erosions can cause de novo dyspareunie. Accordingly, the standard of review is de novo. Editor Schneider presents this bioorganic synthesis volume focusing on de novo computer-assisted design. The Court's role is to consider these decisions on a de novo basis. Chondrosarcomas may arise de novo, or superimposed upon preexisting cartilaginous lesions, such as enchondromas or osteochondromas. It noted that some applications might be for orders that were so different from the original that the matter should be treated as an application for access de novo. Show More Sentences It also exercises the jurisdiction to order the issue of writs of venire de novo. The District Court reviews the facts of the matter de novo. Whenever a repleader is granted, the pleadings must begin de novo. Many states provide the parties with the right to trial de novo once in state court, even if the parties have undergone an administrative hearing or trial. Traditional teaching about the pathogenesis of ovarian cancers has been that a metaplastic change in the mesothelial ovarian surface leads to their de novo development. We note how de novo mutations may also help explain why the concordance rate for autism is so markedly higher in monozygotic than dizygotic twins. Examples from Classical Literature I have adventured to publish it de novo in this book, first because it was but hudled up among purposes of another nature. It would not be more wonderful, de novo, than the discovery of the lightning-rod, or navigation by steam! First, I will give you a translation, de novo, of this untranslateable prayer. Food and Drug Administration regarding its 510 submission and will now proceed with a de novo submission. Food and Drug Administration recently released a revised guidance document addressing the de novo premarket review pathway for medical devices. Robinette wanted a de novo review on the grounds the tax liability was at issue. Therefore, both programs' objectives include a balanced portfolio of projects developing both de novo and re-sequencing technologies. Find more words! 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What is the opposite of de novo? Words that rhyme with de novo Use our Sentence Generator Nearby Words denouncing denounces denouncer denouncements denouncement denounced dens dense dense fog densely densely populated denseness