| This biomarker group is, like the steranes, characterized by numerous maturity-sensitive stereoisomers. |
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| Several biomarker studies have examined the impact of vitamin E supplementation on biomarkers of DNA damage. |
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| Plasma concentration of homocysteine is a good biomarker for folate deficiency. |
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| Therefore, if vitellin and CMP synthesis are under similar hormonal control, CMP expression may serve as a biomarker of endocrine disruption. |
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| Establishment of an early and reliable biomarker for oral carcinogenesis will enable early diagnosis of cancer. |
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| Presently, this alkaloid in urine is the biomarker of choice, given its specificity and relatively long half-life. |
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| Sediments on lake bottoms and sea beds are far richer in biomarker molecules than we might suspect. |
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| Molecular diagnostics is a branch of clinical diagnostics that uses primarily DNA or RNA as a biomarker for clinical testing. |
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| Cytogenetic damage, evaluated as chromosomal aberrations, has been successfully applied as a reliable biomarker for chronic health risk. |
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| They assayed the fish plasma for the estrogenic biomarker, vitellogenin, the major egg-yolk protein under synthesis control of endogenous estradiol. |
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| To detect potentially deadly recurrences, doctors monitored a known biomarker, a calcium-controlling hormone called calcitonin, in the boy's blood. |
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| Genizon BioSciences is an industry leader in genetic biomarker discovery, with programs in 25 common diseases. |
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| Institut Curie researchers are looking for a biomarker that can tell them whether a uveal tumor is likely to spread, or not. |
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| Our proprietary industrialized biomarker discovery platform is GLP and GCP compliant. |
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| These data sets often consist of biomarker responses covering all the levels of biological organization in a vast array of bioindicator organisms representing different trophic levels. |
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| This finding allowed her to produce what is known as a biomarker profile for the illness. |
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| To assess p97 as a biomarker for AD, serum will be collected from the Tg2576 mouse and littermates, each month for 12 months. |
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| In mussels, the proliferation of peroxisomes has been proposed as a specific biomarker of pollution by xenobiotics in marine and estuarine environments. |
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| The authors say that cotinine is a poor biomarker of carcinogenic risk. |
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| In some cases, additional analyses are done for cadmium in blood, a biomarker that better reflects recent cadmium exposure. |
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| The academic community has little experience or training in the rigorous process of biomarker development. |
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| Since cadmium in urine is a life time biomarker of exposure, these higher readings reflect past exposures. |
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| A specific genetic biomarker has recently been identified which predicts the risk of severe liver injury in patients. |
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| This algorithm was used successfully to generate several robust biomarker sets that correlate with patient survival in breast cancer. |
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| It is especially a novel biomarker of heart failure development and progression. |
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| A biomarker is a certain biological element that undergoes change when exposed to a stressor, such as chemical contamination. |
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| Emerging knowledge about zinc, especially zinc fingers, may lead to a new biomarker of zinc status. |
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| We also divided each biomarker into quartiles on the basis of its distribution among controls and compared hypertension risk factors. |
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| We observed a washout effect with decreased biomarker concentrations after repeated lavages following exposure to air. |
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| This is the first reported use of CD3 as a biomarker for T-cell lymphopenia in an immunoassay of Guthrie specimens. |
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| Expression of Engrailed-2 protein in bladder cancer and its potential utility as a urinary diagnostic biomarker. |
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| They said the biomarker was present in cerebral spinal fluid at least 10 years before first signs of dementia set in. |
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| Characterization of pepsinogen C as a potential biomarker for gastric cancer using a histo-proteomic approach. |
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| Evidence suggests that zinc in prostatic fluid correlates with prostate cancer, and it has been identified as a potential biomarker for the disease. |
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| Developments in biomarker science, including research in genomics, metabolomics and imaging, hold promise for improved health and health care through more effective prediction, prevention, prognostication and treatment. |
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| The characteristics of an ideal biomarker of kidney diseases and statistical analysis of biomarker studies is detailed. |
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| Over the course of the decade, the emphasis will gradually shift from biomarker discovery to biomarker validation. |
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| Browse more than 111 market data tables and in-depth TOC on biomarker market. |
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| Antibodies to the Epstein-Barr virus transactivator protein as a valuable biomarker in young patients with nasopharyngeal carcinoma. |
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| For example, once a researcher has identified a promising biomarker, the pathway to clinical validation is not as clearly delineated as that for new drug development. |
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| A modification of this is to place 'caged' micro-organisms in the environment of interest, and to measure biomarker responses following a pre-determined period of time. |
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| This clearly emphasizes the im-portance of POLA2 as a potential biomarker. |
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| Measurement of vitellogenin, a biomarker for exposure to oestrogenic chemicals, in a wide variety of cyprinid fish. |
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| Vitellogenesis as a biomarker for estrogenic contamination of the aquatic environment. |
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| However, the rapid oxidation of NO by certain oxidants may complicate its utility as a biomarker. |
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| The Early Lung Cancer Detection Study is evaluating the effectiveness of identifying high-risk individuals using questionnaires, a spirometry breathing test and a blood biomarker test. |
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| It has been found to be synthesized by osteoarthritic chondrocytes in diseased cartilage and may serve as a specific arthritis biomarker that reflects an attempt by the chondrocytes to repair diseased cartilage. |
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| In addition, the increase in ER? transcripts concomitant with vitellogenin transcripts suggests that ER? may also be a sensitive biomarker of xenoestrogen exposure in this teleost model. |
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| The latest move is towards biomarker data. |
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| Which is awkward, as methane is found in atmospheres, such as that of Saturn's moon Titan, where life is not thought to be present. Another biomarker might be a planet's colour. |
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| Closely linked to care centers, benefiting from a privileged access to biological devices and clinical data from patients under treatment, public research on biomarker identification is a highly dynamic sector. |
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| In the development of companion diagnostics, Ipsogen integrates the complete value chain, from biomarker discovery to regulatory approved IVD tests. |
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| The biomarker initiative will focus on studies of the detection and therapeutic aspects of cancer control, and projects have already been identified for lymphoma and leukemia, and breast, ovarian, lung and prostate cancers. |
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| Every drug being developed at Roche has a biomarker program associated with it, and diagnostics expertise and advice are made available for each of these programs. |
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| In addition to the completion of detailed questionnaires, recruits to the cohort would donate biological samples, such as blood, for future biomarker and gene-environment studies. |
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| In the clinic, biomarker tests increasingly provide invaluable information for early diagnosis and about disease predisposition, prognosis and the likelihood of treatment response. |
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| Medinet laboratory in Aurora provides innovative mass spectrometry-based technologies for the development, validation and measurement of biomarkers and biomarker strategies. |
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| Solvay has already taken a series of measures to adapt to the new situation especially with the acquisition of Innogenetics, which gives us access to key biomarker technology. |
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| Characterization of GD3 ganglioside as a novel biomarker of mouse neural stem cells. |
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| The cardiac biomarker N-terminal proBNP and echocardiographic changes were monitored and mortalities were registered. |
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| Although oxidative stress appears to be a critical mechanism by which exposure to PM causes adverse health effects, its use as a biomarker of exposure has been limited. |
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| The relationship between lysosomal biomarker and organismal responses in an acute toxicity test with Eisenia fetida exposed to the fungicide copper oxychloride. |
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| In this study, we investigated Physa acuta, a freshwater pulmonate with a sinistrally coiled shell, to determine its possible role as a biomarker. |
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| Proteomic characterization of the interstitial fluid perfusing the breast tumor microenvironment a novel resource for biomarker and therapeutic target discovery. |
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| Over the last decade the biomarker model has resulted in considerable research enterprise and nourished and challenged the emerging field of molecular epidemiology. |
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| They cover tools for discovering biomarkers, biomarkers for injury or disease, technology for detecting biomarkers, and hot topics in biomarker research. |
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| Epigenomics is very successfully engaged in epigenetic research since 1998 resulting in an outstanding proprietary platform for epigenetic biomarker discovery for cancer. |
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| Here we show that erythema resulting from UVR is a comprehensive and noninvasive biomarker for assessing UVR damage and can be precisely and easily quantified in human skin. |
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| Immunohistochemistry remains the most widely used method to detect and characterise proteins in tissues in biomarker research and clinical trials. |
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| Telomere length is considered a biomarker of aging, with shorter telomeres associated with a decreased life expectancy and increased rates of chronic disease development. |
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| Data analysis confirmed a consistent, quantifiable defect in sweat gland function as a disease biomarker in XLHED patients, even in the setting of normal sweat pore counts. |
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| New septic shock biomarker test could boost better interventions. |
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