| Sulfapyridine is a competitive inhibitor of bacterial para-aminobenzoic acid, a substrate of the enzyme dihydropteroate synthetase. |
| Thus, the enzymes nicotinic acid mononucleotide adenylyltransferase and NAD synthetase are essential for growth of E. coli. |
| The main substrates are myristate and palmitate, which are produced by a fatty acid synthetase. |
| Ammonium is then incorporated into amino acids via glutamine synthetase and glutamate synthase. |
| It appears that, in the absence of RelA, this novel ppGpp synthetase most likely produces a large quantity of ppGpp, which is toxic to cells. |
| Rifampin has enzyme-inducing properties including induction of delta aminolevulinic acid synthetase. |
