| Dogs showed tubular degeneration and oligospermia in the epididymus in the 12-month toxicity study. |
| In patients with azoospermia or severe oligospermia, the karyotype should be determined because of the increased incidence of karyotypic abnormalities in this population. |
| Men with nonobstructive azoospermia and severe ogliospermia should be informed of the potential genetic abnormalities associated with azoospermia or severe oligospermia. |
| Similar effects on oligospermia and conception rates have been reported in other preliminary trials. |
| In high-dose males, a decrease in testes weights, testicular atrophy and atrophy of the seminal vesicles and prostate, aspermia or oligospermia in the epididymides were observed. |
| The use of sulphasalazine, the oldest of these, has become less popular because of side effects including nausea, skin rashes, and reversible oligospermia. |
