The integrity of the gastrointestinal system is vital to preventing formation and release of exotoxins into systemic circulation. |
Chemical mediators are released that secrete pyrogenic endotoxins and exotoxins. |
The pyrogenic exotoxins, also known as erythrogenic toxins, are responsible for the rash of scarlet fever. |
More strikingly, the exotoxins produced by many pathogenic bacteria are encoded in the genome of lysogenic phages. |
The streptococcal pyrogenic exotoxins together with the staphylococcal enterotoxin build a large family of bacterial superantigens. |