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What is the opposite of inconsequentially?

Need antonyms for inconsequentially? Here's a list of opposite words from our thesaurus that you can use instead.

Adverb
Opposite of in an inconsequential manner
Adverb
In a sufficiently great or important way as to be worthy of attention
“He consumes a significantly large number of calories, but remains trim by being active.”
Adverb
In a telling manner
“Hillary looked up at Don significantly, raising her eyebrow.”
Adverb
Opposite of adverb for lacking sense or sound reasoning
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