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What does up and running mean?

Looking for the meaning or definition of the word up and running? Here's what it means.

Adjective
  1. (idiomatic) operational, in operation
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Examples
Her current assignment is getting the new flagship store up and running well in time for Christmas.
She could be dead asleep, but if she hears a pin drop in the hallway, she's up and running to the door, barking like a madman.
The Treasury has promised that the first Child Trust Fund accounts will be up and running by April 2005 at the latest.
To get this kind of software up and running you have to get your fingers dirty, messing with the innards of Internet servers.
Once up and running, the Government funds them directly and the sponsor controls the academy independently of the local authority.
I've managed to rebuild everything, but as I got the ship up and running it sent out the distress signal.

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