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What is spiro?

What is spiro? Here are some definitions.

Noun
  1. (slang) Spironolactone.
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Examples
Ms. Spiro is most engagingly met by a cast that doesn't try to distort the musical in any way beyond playing it for real, Akiya Henry's chirrupy Minnie Fay a rare performing misstep.
Jarmo Levonen, Jean-Francois Rouet, Andrew Dillon, and Rand Spiro.
It doesn't help that the show's star, the perky Jordana Spiro, best known for comedy My Boys, makes one of the least believable screen doctors ever.
Bill casually proposes to Hillary as the resignation of Vice President spiro Agnew plays in the background.
The first, Spiro Agnew, won in 1966 as the liberal running against a segregationist Democrat.
I will not kill myself because then I should go to hell-fire, but spiro can do it very well.

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