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What does severe mean?

Looking for the meaning or definition of the word severe? Here's what it means.

Adjective
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Clinical clues to possible hyperandrogenism in women include dysmenorrhea, virilization, and severe acne.
Patients who are immunocompromised or who have undergone a splenectomy are at increased risk for severe complications.
Ebola hemorrhagic fever is a severe, often-fatal disease that affects humans and non-human primates, such as monkeys, gorillas and chimpanzees.
For example, nondisclosure could be considered reasonable in the case of a patient with severe depression who was at risk of attempting suicide.
The splenic artery was encased by tumor, although there was no intraluminal invasion, and the artery showed severe calcific atherosclerosis.
Clearly, there is much to do both epidemiologically and virologically to contain the global spread of severe acute respiratory syndrome.

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