The human reovirus infects and kills cancer cells with an activated Ras pathway. |
Oncolytics Biotech has been developing a method of utilizing a reovirus to target and kill cancers that exhibit mutated RAS pathway activity. |
This article describes the characterization of 4 double-stranded ribonucleic acid segments, S1, S2, S3, and S4, of a newly identified pathogenic reovirus from parrots. |
The investigators tested reovirus in vitro against recently resected colorectal cancer liver metastases. |
As such, recent research has focused on reovirus type 3 and cytomegalovirus as possible viral agents. |
The claims cover methods of selectively removing cancer cells ex vivo from blood stem cells and other organs using reovirus. |