| Blood work, including rapid plasma reagin for syphilis and heavy metal screening, had been reported as normal. |
| However, both RPR and VDRL are useful only after the body has a sufficient amount of time to generate a detectable amount of reagin, which usually occurs several weeks following the appearance of a chancre in primary disease. |
| In RPR and VDRL the detection of syphilis reagin is based on the reaction of reagin with a lipid antigen usually extracted from beef heart to produce a visible clumping, or flocculation, within the serum. |
| This reaction is the basis of traditional nontreponemal tests such as the VDRL test and rapid plasma reagin test. |
| The mother was O Rh-positive, antibody screen negative, rapid plasma reagin nonreactive, hepatitis B surface antigen negative. |
| The results of a VDRL test and rapid plasma reagin were negative. |
