| Individuals with GSD-1a display hypoglycemia, hepatomegaly, nephromegaly, hyperlipidemia, hyperuricemia, lactic acidemia and growth retardation. |
| In particular, in cases with concomitant elevated uric acid and nephromegaly the diagnosis of renal lymphoma should always be a consideration. |
| Leukemia may also appear as bilateral or unilateral nephromegaly. |
| Renal lymphoma most often manifests as multiple bilateral renal masses and occasionally, nephromegaly. |
| The patients manifest hypoglycemia, growth retardation, hepatomegaly and nephromegaly with consequent compromised liver and kidney functions. |
