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What is a necrosis?

What is a necrosis? Here are some definitions.

Noun
  1. (pathology) The localized death of cells or tissues through injury, disease, or the interruption of blood supply.
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Examples
The venom consists of proteins, polypeptides, and enzymes that cause necrosis and hemolysis.
There was extensive but patchy acinar atrophy and parenchymal fibrosis, but no evidence of fat necrosis, pseudocyst formation, or calculi.
Alternatively, infiltrating microglia near a focus of radiation necrosis may be mistaken for a malignancy in a treated glioma.
I was once called to give an opinion over a case of femoral necrosis with suppuration following coxalgia in a young boy.
Circulating concentrations of the cytokine tumour necrosis factor are increased in cachectic patients with chronic heart failure.
The venom has vasoconstrictive properties that can lead to cyanosis and necrosis, with poor wound healing and infection.

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