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What is a myxoedema?

What is a myxoedema? Here are some definitions.

Noun
  1. Alternative spelling of myxedema
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Examples
The same may be said also of the different forms of cerebral and spinal sclerosis, of pernicious anmia, and of myxoedema.
Pretibial myxoedema is a known manifestation of Graves' disease that occurs in association with diffuse thyroid gland enlargement, exophthalmos, and thyroid acropachy.
In myxoedema there is a swelling or general enlargement, especially of the upper portions of the trunk.
Doniach postulated that Addison's disease, thyrotoxicosis, myxoedema, pernicious anaemia, and hypoparathyroidism might have the same aetiology.
A firm enlargement of the surface of the face and upper part of the body occurs in myxoedema.
I changed my hairdresser but the possibility of myxoedema did not enter my head.

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