| So tell me how a simple point mutation changes the information content of the gene. |
| We are studying properties of spontaneous mutation affecting quantitative traits of the annual crucifer, Arabidopsis thaliana. |
| This frameshift mutation could be merely drifting to high frequency due to weak functional constraint. |
| We estimate that reversion of the lac mutation is about one-tenth as likely as a null frameshift mutation in a typical gene. |
| Every known mutation has either decreased information content or was informationally neutral. |
| Arrows indicate the position of the point mutation and the corresponding nucleotide on the wild-type sequence. |
