| Although no confirmed cases of WNV-attributed disease have been reported in Central America to date, flavivirus transmission appears to be widely distributed in Guatemala. |
| Safety issues with the live flavivirus vaccines need to be recognised and addressed. |
| West Nile virus is a single-stranded RNA flavivirus with antigenic similarities to Japanese encephalitis and St. Louis encephalitis viruses. |
| Louping ill is a zoonotic disease caused by a neurotropic, single-stranded, 40 to 50-nm RNA virus, which has been classified in the family Flaviviridae, genus Flavivirus. |
| Japanese encephalitis virus is the most important and widespread flavivirus in terms of human morbidity and mortality. |
| The causative agents are four closely related, but antigenically distinct, virus serotypes of the genus Flavivirus. |
