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What does demasculinize mean?

Looking for the meaning or definition of the word demasculinize? Here's what it means.

Verb
  1. To remove the testicles from
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Examples
In general, ovarian estrogens feminize and demasculinize the developing hypothalamus and perhaps other brain areas known to control copulatory behaviors.
When delivered to pregnant rats, a very low dose of dioxin can not only demasculinize but also feminize the sexual development of male offspring, a trio of new studies shows.

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