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What is a dedifferentiation?

What is a dedifferentiation? Here are some definitions.

Noun
  1. The loss or reversal of differentiation.
  2. (biology) The biological process whereby cells revert from a specialized function to a simpler or less specialized form.
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Examples
This probably reflects the presence of stem cells in the nail bud rather than cell dedifferentiation.
Thus, the dedifferentiation of chondroid cells was relative to the decrease of cell surface proteins.
Researchers have also been able to generate cardiac stem cells for the treatment of certain forms of heart disease through the process of dedifferentiation, in which mature heart cells are stimulated to revert to stem cells.
Zebra fish and mammals are separated by a long evolutionary distance and yet, surprisingly, the first step in the regeneration process, the dedifferentiation of heart muscle cells, occurs in mammals as well.
Cardiac stem cells can be derived from mature cardiomyocytes through the process of dedifferentiation, in which mature heart cells are stimulated to revert to a stem cell state.
What steps in regeneration follow dedifferentiation? 3. Explain to students that today they will be preparing to make presentations on certain organisms that currently have the ability to regenerate body parts.

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