| Of the abnormalities noted, the cytopenias and abnormalities of liver function showed dose-related differences. |
| However, the occurrence of cytopenias was also clearly dependent on the stage of the disease. |
| Dosages and schedules must be adjusted to prevent life-threatening cytopenias whenever these adverse reactions are observed. |
| Patients suffer from autoimmune cytopenias and rheumatoid arthritis, which are thought to be mediated by LGL cells targeting host tissues. |
| The time to nadir was 4 to 7 weeks and the duration of cytopenias was approximately 30 days. |
| Due to the variable nature in the onset of cytopenias, complete blood counts should be obtained weekly following BEXXAR® and should continue until levels recover. |
