This interesting work shows that exactly the right purified solution of linear organic molecules can cyclize under the right conditions to present activated nucleotides. |
The 2-aminophenoxy groups predispose the oligomers to cyclize as amic acids, and to remain as cyclics on imidization. |
On the other hand, seco-acid derivative having tertiary alcohol at C8 was predicted not to cyclize to form macrolactone. |
The biradical can revert to the starting material, cyclize to give a cyclobutanol derivative, or in our case, fragment to an alkene and an enol component. |
These extensions, called cohesive ends, are complementary and enable the chromosome to cyclize in an infected cell. |
Four molecules of this porphyrin precursor cyclize and undergo several side-chain modifications to yield the tetrapyrrole protoporphyrin. |