Use of a chemokine receptor antagonist in combination with a cyclosporin to produce a pharmaceutical composition for treating or preventing the rejection of tranplanted organs, tissues or cells. |
To take an example, the famous Human Genome Sciences patent 6,025,154 claims an isolated nucleotide molecule encoding the amino acids of what was designated as a chemokine receptor. |
These are messenger molecules that attract immune cells to the chemokine source. |
The blood vessels that form to nourish a growing brain tumor apparently secrete the receptors chemokine. |
Once the cancer cells bind to CXCL12 in the new tissue site, the chemokine stimulates tissue activities that promote the survival of the cancer cells. |
Use of an adsorbent which comprises a solid material having an anionic functional group for the preparation of a pharmaceutical composition for removing from body fluid a chemokine classified into CC subfamily. |