But embryonic cardiomyocytes can multiply, with embryonic stem cells providing an endless reservoir for new cardiac tissue. |
Dioxin exposure disrupts the differentiation of mouse embryonic stem cells into cardiomyocytes. |
In Tokyo, scientists have developed a technique for wrapping a thin sheet of cardiomyocytes — muscle cells that the heart needs in order to beat — around the severely damaged hearts of patients. |
They stop beating long enough to divide and provide the heart with fresh cardiomyocytes. |
The scientists found that new heart cells were generated from pre-existing cardiomyocytes rather than progenitor cells. |
To test the behavior of the grafted cells we have developed a model of heart organotypic culture and showed that the cells effectively differentiate into cardiomyocytes and are integrated into the host tissue. |