However during this biotransformation process, generation of reactive metabolites might result in toxicity and liver cell damage. |
Other recognized factors leading to medication allergy are pre-existing allergies and presence of diseases that interfere with medication biotransformation and excretion. |
These results are in contrast with reports of enantioselective biotransformation in other species. |
Methylation is not as important a route of biotransformation for exogenous chemicals as it is for endogenous chemicals. |
Differences in placental membranes, placental transport and biotransformation all affect fetal exposure. |
Altering the metabolism of and biotransformation processes for serotonin may be an important feature for the treatment of depression. |