Furthermore, we expect that small anharmonic corrections present in both the native and the random states will cancel out. |
Some studies have found a relationship between the onset of anharmonic motion and activity of proteins. |
Such curves are not characterized by parabolic functions, indicating that hydrogen-bonding interactions are strongly anharmonic. |
For an anharmonic potential, the spacing between modes changes as energy increases. |
It was successfully fitted to the anharmonic coupling model, the fitting parameters being close to those obtained earlier. |
The anharmonic dynamics involve diffusive motion and allow sampling of different conformational substates. |