| Health care professionals should be aware of the risk of agranulocytosis suspected of being associated with atypical antipsychotics. |
| Hematologic Reactions: Leukopenia, agranulocytosis, hemolytic anemia, thrombocytopenia, aplastic anemia, erythrocytopenia, granulocytopenia, and pancytopenia have been reported with sulfonylureas, including glimepiride. |
| One of the major risks associated with the use of clozapine is the potential for patients to develop agranulocytosis. |
| When reviewers repeated the trial years later, in a larger population, they found the incidence of this agranulocytosis was much lower than previously thought. |
| Bone marrow biopsy and other hematologic tests were consistent with agranulocytosis and marked erythroid hypoplasia of the megakaryocyte type. |
| Thirteen of the 32 reports found were of platelet, bleeding or clotting disorders, and 4 were of granulocytopenia or agranulocytosis, for a total of 17 reports of serious or fatal hematologic reactions. |
